Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse fibroblasts to examine the cellular transformation induced by Rho subfamily GTPases
We have used microarray technology to identify the transcriptional targets of Rho subfamily GTPases. This analysis indicated that murine fibroblasts transformed by these proteins show similar transcriptomal profiles. Functional annotation of the regulated genes indicate that Rho subfamily GTPases ...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5913 | biostudies-arrayexpress
ProteomicsSRGAP1 controls small Rho GTPases to regulate podocyte foot process maintenance
Podocyte foot process effacement and proteinuria is a common and uniform consequence of glomerular injury. Previously it has been shown that small Rho GTPases (e.g. RAC1) are drivers of podocyte foot process effacement in glomerular diseases such as focal segmental glomerulosclerosis (FSGS). However...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-30 | MSV000085853 | MassIVE
GenomicsIRE1alpha cancer mutants diiferentially regulate Rho family GTPases
IRE1alpha cancer mutants diiferentially regulate Rho family GTPases
PRJNA1166305 | ENA
GenomicsHP1γ/CBX3 Promotes Lung Adenocarcinoma by Activating Rho GTPases Signaling Pathway
HP1γ/CBX3 Promotes Lung Adenocarcinoma by Activating Rho GTPases Signaling Pathway
PRJNA727321 | ENA
TranscriptomicsTranscriptional profiling of the cellular transformation induced by Rho subfamily GTPases
We have used microarray technology to identify the transcriptional targets of Rho subfamily GTPases. This analysis indicated that murine fibroblasts transformed by these proteins show similar transcriptomal profiles. Functional annotation of the regulated genes indicate that Rho subfamily GTPases ta...
ORGANISM(S): Mus musculus 
2007-01-03 | GSE5913 | GEO
TranscriptomicsIRE1alpha cancer mutants diiferentially regulate Rho family GTPases
IRE1alpha is a multi-domain, ER-transmembrane protein that can mediate the Unfolded Protein Response (UPR). Here, we show that cancer-specific mutations in IRE1alpha can differentially activate the Rho family GTPases to mediate tumor promoting events in mouse keratinocytes.
ORGANISM(S): Mus musculus 
2025-08-06 | GSE278307 | GEO
ModelsOta2015 - Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs (GDI integrated)
This is a ordinary differential equation mathematical model describing the Rho GTPase cycle in which Rho GDP-dissociation inhibitors (RhoGDIs) inhibit the regulatory activities of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs) by interacting with them directly as we...
2024-09-02 | BIOMD0000000899 | BioModels
TranscriptomicsHP1γ/CBX3 Promotes Lung Adenocarcinoma by Activating Rho GTPases Signaling Pathway
We performed CBX3 knockdown in lung adenocarcinoma cells along with RNA sequencing. The expression profiling showed Rho GTPases signaling as a potential CBX3 target and the conclusions were also verified in clinical samples.
ORGANISM(S): Homo sapiens 
2021-05-05 | GSE173858 | GEO
TranscriptomicsTranscription profiling of mouse primary keratinocytes expressing Rho/CRIK to study the impact of Rho signaling pathway on gene expression.
Rho GTPases integrate control of cell structure and adhesion with downstream signaling events. In keratinocytes, RhoA is activated at early times of differentiation and plays an essential function in establishment of cell–cell adhesion. We report here that, surprisingly, Rho signaling suppresses dow...
ORGANISM(S): Mus musculus 
2007-09-07 | E-GEOD-3162 | biostudies-arrayexpress
UnknownRho GTPases, oxidation, and cell redox control.
Not available
S-EPMC4114927 | biostudies-literature
Sort   by:  
 Page size