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OtherGlobal mass spectrometry and transcriptomics array based drug profiling provides novel insight into glucosamine induced ER stress.
Data from ProteomeXchange, PXD ID: PXD000380. Experiment: Treatment, file: MS12236QE_rune_henrik_Treatment_c.mzml. Published as part of Mol Cell Proteomics. 2014 Aug 15 . From the Abstract: {{i}} We investigated the molecular effects of glucosamine supplements, a popular and safe alternative to non...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310003280 | GPMDB
Resource Reanalysis 
UnknownEndophytic bacterial diversity in banana 'Prata Ana' (Musa spp.) roots.
Not available
S-EPMC3715292 | biostudies-literature
TranscriptomicsTranscription profiling of mouse HOXB4 in adult hematopoietic stem and progenitor cells with inducible HOXB4 to identify its target genes
HOXB4 mediates expansion of adult and embryo-derived hematopoietic stem cells (HSCs) when expressed ectopically. To define the underlying molecular mechanisms, we performed gene expression profiling in combination with subsequent functional analysis using enriched adult HSCs expressing inducible HO...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9010 | biostudies-arrayexpress
ProteomicsTauroursodeoxycholic acid-induced neural stem cell proliferation
Tauroursodeoxycholic acid (TUDCA), an endogenous neuroprotective bile acid and a metabolic regulator, stimulates NSC proliferation and enhances adult NSC pool in vitro and in vivo. In this study, we dissected the mechanism triggered by this proliferation-inducing molecule, namely in mediating metabo...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD017979 | Pride
Lc-msms Mouse Neuronal stem cells 
TranscriptomicsGene exrpression profiling of childhood adrenocortical tumors
Pediatric adrenocortical tumors (ACT) are rare and often fatal malignancies; little is known regarding their etiology and biology. To provide additional insight into the nature of ACT, we determined the gene expression profiles of 24 pediatric tumors (five adenomas, 18 carcinomas, and one undetermin...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75415 | biostudies-arrayexpress
ProteomicsMolecular signatures of Haemonchus contortus infection in sheep: a serum proteomics study on susceptible and tolerant sheep breeds
Haemonchus contortus is the gastrointestinal nematode (GIN) species that most parasites sheep and goats in tropical and subtropical regions. Due to the high prevalence and pathogenicity by hematophagy, it causes severe anemia, submandibular edema and deaths. Post-genomics tools, such as proteomics, ...
ORGANISM(S): Ovis aries 
2024-11-25 | PXD048967 | Pride
Host resistance Haemonchus contortus Proteomics Dorper Santa inês Sheep 
TranscriptomicsscRNA-seq of human Tfh, Tfr and Treg cells sorted from Tonsil, Iliac Lymph Node and PBMCs
The datasets were obtained to investigate the transcriptional profile of Tfh, Tfr and Treg cells isolated from different human tissues. The comparison between lymphoid tissues with different frequency of the most mature Tfh and Tfr cells allows the investigation of maturation as well as tissue adapt...
ORGANISM(S): Homo sapiens 
2021-04-22 | E-MTAB-10364 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of breast cancer cell lines with different levels of P-cadherin expression treated with the anti-cancer bacterial protein azurin
We performed a microarray analysis to compare the expression profile of azurin treated and untreated with different P-cadherin expression levels. We also compared the differentially expressed genes regulated by P-cadherin overexpression. Both cell lines presented an up-regulation of apoptosis mediat...
ORGANISM(S): Homo sapiens 
2014-04-30 | E-GEOD-54319 | biostudies-arrayexpress
ProteomicsSyndecan-4 is a maestro of gastric cancer cell invasion and communication that underscores poor survival
Gastric cancer is a dominating cause of cancer-associated mortality with limited therapeutic options. Here, we show that syndecan-4 (SDC4), a plasma membrane proteoglycan, is highly expressed in intestinal subtype gastric tumours and that this signature associates with patients’ poor survival. Furth...
ORGANISM(S): Homo sapiens (Human) 
2023-05-05 | PXD035679 | Pride
Extracellular vesicles Extracellular communication Gastric cancer Syndecan-4 Heparan sulfate proteoglycans Cancer cell invasion 
TranscriptomicsTrancriptome analysis of peripheral leukocytes from SARS-CoV-2 infected patients and healthy uninfected individuals during the first wave of COVID-19 pandemic in Brazil
To evaluate the gene expression profiling of peripheral leukocytes in different outcomes of SARS-CoV-2 infections, whole blood samples were collected from individuals with positive SARS-CoV-2 nasopharyngeal swab by RT-PCR (54 patients) and healthy uninfected individuals (12 volunteers). Infected pat...
ORGANISM(S): Homo sapiens 
2022-04-29 | E-MTAB-11240 | biostudies-arrayexpress
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