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MetabolomicsMetabolomics Insights in Early Childhood Caries
Dental caries is characterized by a dysbiotic shift at the biofilm-tooth surface interface, yet comprehensive biochemical characterizations of the biofilm are scant. We used metabolomics to identify biochemical features of the supragingival biofilm associated with early childhood caries (ECC) preval...
2021-01-29 | MTBLS2215 | MetaboLights
UnknownAnalysis of the Plasmodium and Anopheles transcriptomes during oocyst differentiation.
Not available
S-EPMC4674691 | biostudies-literature
ProteomicsA substrate-like thrombin inhibitor from the saliva of the flea Xenopsylla cheopis is resistant to cleavage by the enzyme
XC-43 is a small peptide identified in the sialome of the flea Xenopsylla cheopis and act as a fast, tight-binding inhibitor of thrombin with a dissociation constant of less than 10 pM. The crystal structure of XC-43 in complex with thrombin shows that despite its substrate-like binding mode, XC-43 ...
ORGANISM(S): Xenopsylla cheopis 
2022-02-16 | PXD028851 | Pride
Flea Blood feeding X-ray crystallography Thrombin 
MetabolomicsUntargeted metabolomics sheds light on the secondary metabolism of fungi triggered by choline-based ionic liquids
Fungal secondary metabolites constitute a rich source of yet undiscovered bioactive compounds. Their production is often silent under standard laboratory conditions, but the production of some compounds can be triggered simply by altering the cultivation conditions. The usage of an organic salt - io...
2022-07-15 | MTBLS5072 | MetaboLights
Transcriptomicsarray-CGH profiling of human neuroblastoma samples obtained from infants included in the INES99.1, INES99.2 and INES99.3 trials
In neuroblastoma (NB), the presence of segmental chromosome alterations (SCA) is associated with a higher risk of relapse, even when occurring together with numerical chromosome alterations (NCA). Furthermore, recent evidence shows that SCAs play a role in tumor progression. In order to analyze the ...
ORGANISM(S): Homo sapiens 
2011-12-07 | E-GEOD-26494 | biostudies-arrayexpress
UnknownEnzyme Characterization of Pro-virulent SntA, a Cell Wall-Anchored Protein of Streptococcus suis, With Phosphodiesterase Activity on cyclic-di-AMP at a Level Suited to Limit the Innate Immune System.
Not available
S-EPMC8981391 | biostudies-literature
ProteomicsThe immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus
Ticks are obligate hematophagous arthropods that transmit a wide range of pathogens to humans as well as wild and domestic animals. They also harbor a non-pathogenic microbiota, although our previous study has shown that the diverse bacterial microbiome in the midgut of Ixodes ricinus is quantitativ...
ORGANISM(S): Ixodes ricinus 
2024-10-17 | PXD053128 | Pride
Midgut microbiome Defensin Immune system Antimicrobial peptide Micrococcus luteus Tick Ixodes 
ProteomicsTick (Ixodes ricinus) salivary antigens by LC-MS/MS
Here, we challenged rabbits with repeated feeding of Ixodes ricinus adults and observed the formation of specific antibodies against several tick salivary proteins. To identify the salivary antigens, isolated immunoglobulins from repeatedly infested rabbits were utilised for a pull-down from the sal...
ORGANISM(S): Homo sapiens (Human) Ixodes ricinus 
2021-09-09 | PXD021370 | Pride
Ticks Antigen Saliva Immunoprecipitation 
UnknownLocal Induction Heating Capabilities of Zeolites Charged with Metal and Oxide MNPs for Application in HDPE Hydrocracking: A Proof of Concept.
Not available
S-EPMC7926789 | biostudies-literature
UnknownHigh dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning.
Not available
S-EPMC10799879 | biostudies-literature
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