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TranscriptomicsIdentification of avian RIG-I responsive genes during influenza infection
Transcriptional profiling of chicken embryonic fibroblasts (DF-1 cells) comparing the effects of chicken cells transfected with duck RIG-I compared to empty-vector transfected cells following with low or highly pathogenic avian influenza. Goal was to determine the effects of duck RIG-I on influenza-...
ORGANISM(S): Gallus gallus 
2012-12-12 | E-GEOD-29596 | biostudies-arrayexpress
TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity [comparison]
The RIG-I like receptor pathway is stimulated during RNA virus infection by interaction between cytosolic RIG-I and viral RNA structures that contain short hairpin dsRNA and 5M-bM-^@M-^Y triphosphate (5M-bM-^@M-^Yppp) terminal structure. In the present study, an RNA agonist of RIG-I was synthesized ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60572 | biostudies-arrayexpress
TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity [Kinetic]
The RIG-I like receptor pathway is stimulated during RNA virus infection by interaction between cytosolic RIG-I and viral RNA structures that contain short hairpin dsRNA and 5M-bM-^@M-^Y triphosphate (5M-bM-^@M-^Yppp) terminal structure. In the present study, an RNA agonist of RIG-I was synthesized ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60573 | biostudies-arrayexpress
ProteomicsHuman Flag-tagged RIG-I IP-MS in HEK293T
nevaeh: The PARP inhibitor olaparib is widely used in cancer but is underused in treating lung adenocarcinoma (LUAD). Our initial analysis revealed that RIG-I, which is typically found in the cytoplasm and activates innate immunity, is linked to LUAD outcome. Here, we discovered that RIG-I undergoes...
ORGANISM(S): Homo sapiens (Human) 
2025-12-10 | PXD058597 | Pride
Hek293t Ip-ms Rig-i 
ProteomicsHuman Flag-tagged RIG-I lactylation IP-MS in HEK293T
The PARP inhibitor olaparib is widely used in cancer but is underused in treating lung adenocarcinoma (LUAD). Our initial analysis revealed that RIG-I, which is typically found in the cytoplasm and activates innate immunity, is linked to LUAD outcome. Here, we discovered that RIG-I undergoes lactyla...
ORGANISM(S): Homo sapiens (Human) 
2025-12-10 | PXD058596 | Pride
Human Hek293t Rig-i 
Transcriptomics3' UTR RNA-sequencing of human lung adenocarcinoma cell lines PC9 and A549 treated with RIG-I agonist IVT4/unspecific control IVT-GAC
The cell lines were treated with RIG-I agonist IVT4 or unspecific control IVT-GAC for 8h and then harvested for 3' UTR RNA-seq analysis
ORGANISM(S): Homo sapiens 
2021-08-09 | E-MTAB-10802 | biostudies-arrayexpress
TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60574 | biostudies-arrayexpress
GenomicsGene expression changes upon activation of RIG-I by a minimal potent RIG-I ligand
Gene expression changes upon activation of RIG-I by a minimal potent RIG-I ligand
PRJNA418284 | ENA
ProteomicsType I interferon/STAT1 signaling negative feedback regulates UBE2M-mediated antiviral innate immunity
To identify potential proteins involved in RIG-I regulation, we pulled down RIG-I from HEK293T or NIH-3T3 cells overexpressing RIG-I, and the RIG-I-bound proteins were then analyzed by mass spectrometry (MS).
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-01-30 | PXD039071 | Pride
Hek293t nih-3t3 lc-msms rig-i ube2m 
ProteomicsIdentification of lysine sites in RIG-I ubiquitinated by RNF167 through mass spectrometry analysis
To identify RNF167-catalyzed ubiquitinated peptides of RIG-I
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060570 | Pride
Lc-ms Ubiquitination 
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