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ProteomicsDevelopment of a Robust Score and False Discovery Rate for Metabolite Identification
We used machine learning (ML) to improve metabolite identification confidence in GC-MS data. This project was funded by PNNL's M/Q initiative. All data was collected on an Agilent GC 7890A coupled with a single quadrupole MSD 5975C. Metabolites were derivatized prior to analysis.
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) Aspergillus (ncbitaxon:5052) Homo Sapiens (ncbitaxon:9606) Aspergillus Nidulans (ncbitaxon:162425) 
2022-07-20 | MSV000089933 | MassIVE
TranscriptomicsGenetic alteration in recurrent melanoma - part 2
Studying a unique case of metastatic melanoma, we observed that cell lines derived from metachronous metastases arising over a decade retained a central core of genetic stability in spite of divergent phenotypes. In the present study we expanded our previous observations comparing these autologous c...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-8778 | biostudies-arrayexpress
UnknownRationally Engineered Tandem Facial Amphiphiles for Improved Membrane Protein Stabilization Efficacy.
Not available
S-EPMC7233144 | biostudies-literature
UnknownA microbial natural product fractionation library screen with HRMS/MS dereplication identifies new lipopeptaibiotics against Candida auris.
Not available
S-EPMC11774467 | biostudies-literature
UnknownDetermination of the critical residues responsible for cardiac myosin binding protein C's interactions.
Not available
S-EPMC3496057 | biostudies-literature
TranscriptomicsTranscription profiling of MDA-MB-231 mammary cancer cells conditionally expressing progesterone receptor isoforms PRA and PRB
The progesterone receptor isoforms PRA and PRB are implicated in breast cancer development and metastasis. Expression ratio PRA/PRB is imbalanced in such cancers under the influence of MAPK-dependent extracellular stimuli that strongly impact progesterone-responsiveM- transcriptional regulation. In...
ORGANISM(S): Homo sapiens 
2012-06-11 | E-TABM-1215 | biostudies-arrayexpress
TranscriptomicsGenetic alteration in recurrent melanoma
It is generally accepted that human cancers derive from a mutated single cell. However, the genetic steps characterizing various stages of progression remain unclear. Studying a unique case of metastatic melanoma, we observed that cell lines derived from metachronous metastases arising over a decade...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-8777 | biostudies-arrayexpress
ProteomicsO-fucosylated glycoproteins of Toxoplasma gondii
The fucose-binding Aleuria aurantia lectin (AAL) labels punctiform structures in proximity to the nuclei of Toxoplasma gondii tachyzoites. We have utilized AAL-lectin affinity purification in conjunction with LC MS/MS to identify a set of proteins modified with fucose on serines and threonines
ORGANISM(S): Toxoplasma gondii 
2016-10-11 | PXD004426 | Pride
Lc ms/ms Aal Affinity purification Fucose Nucleus Toxoplasma gondii Lectin 
TranscriptomicsM.ruminantium_B.proteoclasticus_coculture_vs_monocultures
This study was undertaken with two major goals in mind: i) To investigate the potential for interspecies hydrogen transfer between a hemicellulytic rumen bacterium (B. proteoclasticus) and a methanogenic achaea (M. ruminantium) Microscopic examination had previously shown B. proteoclasticus in co-cu...
ORGANISM(S): Butyrivibrio proteoclasticus B316 
2010-01-27 | E-GEOD-18716 | biostudies-arrayexpress
UnknownImportation of exotic ticks and tick-borne spotted fever group rickettsiae into the United States by migrating songbirds.
Not available
S-EPMC3946858 | biostudies-literature
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