Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact o...
ORGANISM(S): Anopheles gambiae str. PEST Plasmodium berghei ANKA
Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact o...
ORGANISM(S): Anopheles gambiae str. PEST Plasmodium berghei ANKA Plasmodium falciparum NF54
Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact o...
ORGANISM(S): Anopheles gambiae str. PEST Plasmodium berghei ANKA
To identify the putative salivary tPA activator, we fractionated salivary proteins by size-exclusion chromatography and identified fraction Z8 as the strongest tPA activator, whereas the adjacent fractions Z7 and Z9 activated tPA at lower levels. Mass spectrometry analysis of these fractions identif...
Preterm birth (PTB, born before 37 weeks of gestation) is a leading cause of neonatal mortality and post-natal morbidity. PTB affects one in nine all live births in the U.S. Notably, the highest rate of PTB occurs among African Americans (one in six). PTB is a complex trait, likely determined by ...
Acute myeloid leukemia, lymphoma and multiple myeloma cell lines were grown for 24h in RPMI medium and cells were harvested by centrifugation. Samples were digested with trypsin and subjected to phosphoenrichment using IMAC. Phosphopeptides were run in a LTQ-Orbitrap-XL. Peaks lists were generated ...
Gallus gallus avian eggshell is composed of 95% calcium carbonate on calcitic form and of 3.5% extracellular organic matrix (proteins, polysaccharides and proteoglycans). This highly ordered structure with a polycrystalline organization result of the control of mineral deposition by the organic matr...
This a model from the article:
Mechanism for the universal pattern of activity in developing neuronal networks.
Tabak J, Mascagni M, Bertram R. J Neurophysiol
2010 Feb 17; [Epub ahead of print] 20164396
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Abstract:
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Tissue stem cells are hierarchically organized, but the signals that selectively preserve their functional integrity are largely unknown. Semaphorin 4A (Sema4A) is a specific regulator of myeloid-biased hematopoietic stem cells (myHSC), which are positioned at the top of the HSC hierarchy. Through s...
