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ProteomicsG9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered TCR-T cells against hepatocellular carcinoma
Engineered T cells transiently expressing tumor-targeting receptors are an attractive form of engineered T cell therapy as they carry no risk of insertional mutagenesis or long-term adverse side-effects. However, multiple rounds of treatment are often required, increasing patient discomfort and cost...
ORGANISM(S): Homo Sapiens (human) 
2023-01-19 | PXD039542 | JPOST Repository
UnknownRAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han population.
Not available
S-EPMC3942844 | biostudies-literature
TranscriptomicsSingle-cell RNAseq of PBMC from mice infected with Dengue virus
Single-cell RNAseq of PBMC from mice infected with either WT DENV2 or a T209 mutant DENV2
ORGANISM(S): Mus musculus 
2026-04-21 | E-MTAB-15296 | biostudies-arrayexpress
ProteomicsAnti-Toxoplasma gondii effect of vorinostat in vitro and in vivo
Toxoplasma gondii is an important pathogenic protozoon that infects up to one-third of the world's population. In immunocompetent individuals, the infection generally is asymptomatic. However, in immunocompromised patients, the infection can lead to severe and fatal complications. This is due to the...
ORGANISM(S): Toxoplasma Gondii Rh-88 
2024-07-17 | PXD053997 |
UnknownGlycans on Non-Structural Protein 1 Prevent Premature T-cell Mediated Dengue Virus Clearance
Not available
S-SCDT-10_1038-S44321-025-00311-6 | biostudies-other
TranscriptomicsTranscriptional analysis (nCounter Human Immunology v2 Panel) of A549 cells with HMGB1 knockdown and infected with WT or attenuated mutant Dengue virus 2 strains
HMGB1 were silence in A549 cells using siRNA targeting.These A549 cells were then infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different atte...
ORGANISM(S): Homo sapiens 
2026-05-14 | E-MTAB-16204 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of primary human monocyte-derived dendritic cells (moDCs) infected with WT and attenuated mutant Dengue virus 2 strains
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16201 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis (nCounter Human Immunology v2 Panel) of primary human monocyte-derived dendritic cells (moDCs) infected with WT and attenuated mutant Dengue virus 2 strains
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16202 | biostudies-arrayexpress
UnknownA self-amplifying mRNA vaccine expressing PRV gD induces robust immunity against virulent mutants
Not available
S-EPMC12354905 | biostudies-literature
TranscriptomicsEarly Events in Hematopoietic Cells Reprogramming into iPS Cells
Fibroblasts are the most commonly used model in probing the complex process of somatic reprogramming. Although hematopoietic cells represents a more  convenient and accesible/ or “an excellent alternative” starting cell type, the molecular mechanisms in hematopoietic reprogramming are poorly defined...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-54462 | biostudies-arrayexpress
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