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ProteomicsThe p53 Tumor Suppressor Regulates AKR1B1 Expression, a MetastasisPromoting Gene in Breast Cancer
Alteration of metabolism in cancer cells is a central aspect of the mechanisms that sustain aggressive traits. Aldo-keto reductase 1 B1 (AKR1B1) catalyzes the reduction of several aldehydes to alcohols consuming NADPH. Nevertheless, the ability of AKR1B1 to reduce different substrates renders diffic...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-19 | PXD045048 | Pride
Breast cancer Mitochondria Electron transport chain Aldo-keto reductases Akr1b1 Proteomics P53 Metastasis 
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