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ProteomicsiTRAQ analysis of K562 cell line
K562 cells untreated (S) and treated (S+IM) with Imatinib as well as sensitive (S+IM) and resistant (R) to imatinib were subjected to labelled quantification by iTRAQ to identify Bcr-Abl downstream signaling components and proteins modulated in resistance respectively
ORGANISM(S): Homo sapiens (Human) 
2021-10-05 | PXD025173 | Pride
K562 Itraq 
ProteomicsLC-MSMS of leukemic cell line K562
Comparative label free quantitative proteomic analysis using SWATH-MS has been carried out for K562 cells treated with Imatinib (S+IM) against untreated K562 (S) as well as imatinib resistant K562 cells (R). Compariosn of S+IM vs R constitutes Dataset 1 while that of S vs S+IM constitutes dataset 2
ORGANISM(S): Homo sapiens (Human) 
2019-06-14 | PXD009686 | Pride
K562 Swath-ms Lc-msms 
UnknownMultiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development.
Not available
S-EPMC11535547 | biostudies-literature
ProteomicsImmunoprecipitation followed by mass spectrometry (IP-MS)
Immunoprecipitation of ITGB1 and YWHAE was done to understand its interactive partners in K562/S cells. Mass spectrometry was performed to identify interactive molecules. Non-specific proteins (contaminants) such as keratins were excluded from the final analysis based on the results of the negative ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-30 | PXD056828 | Pride
Immunoprecipitation Mass spectrometry Protein-protein interaction Lc-ms/ms 
GenomicsTranscriptomics of K562/S and K562/R, KU812/S and KU812/R of imatinib resistant cell using RNA-sequencing.
Transcriptomics of K562/S and K562/R, KU812/S and KU812/R of imatinib resistant cell using RNA-sequencing.
PRJNA1390135 | ENA
UnknownRegional disparities in antenatal care utilization in Indonesia.
Not available
S-EPMC7018075 | biostudies-literature
UnknownAtypical activation of signaling downstream of inactivated Bcr-Abl mediates chemoresistance in chronic myeloid leukemia.
Not available
S-EPMC8891420 | biostudies-literature
UnknownRegional disparities in hospital utilisation in Indonesia: a cross-sectional analysis data from the 2018 Indonesian Basic Health Survey.
Not available
S-EPMC9815017 | biostudies-literature
UnknownEffects of low and moderate refractive errors on chromatic pupillometry.
Not available
S-EPMC6426861 | biostudies-literature
TranscriptomicsGenomic profiling of immature hematopoietic cells to obtain insights into imatinib resistance
Chronic myeloid leukemia (CML) epitomizes successful targeted therapy, with 86% of patients in the chronic phase treated with tyrosine kinase inhibitors (TKIs) attaining remission. However, resistance to TKIs occurs during treatment, and patients with resistance to TKIs progress to the acute phase c...
ORGANISM(S): Homo sapiens 
2024-01-01 | E-MTAB-11899 | biostudies-arrayexpress
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