Sort   by:  
 Page size 
ProteomicsThe transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis
Changes in epigenetic regulation are believed to be a major contributing factor to neuroblastoma development. Using a large-scale in vivo mutagenesis screen in Th-MYCN transgenic mice, we identified a single point mutation in the transcriptional corepressor Runx1t1, that can block N-myc-driven neuro...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050375 | Pride
Neuroblastoma Mycn Runx1t1 Corest 
TranscriptomicsTranscription profiling of human normal progenitor cells mutated for RUNX1-RUNX1 during myeloid and erythroid development to identify genes disregulated by RUNX1-RUNX1
In order to identify genes dysregulated by the aberrant transcriptional activity of RUNX1-RUNX1T1, we used microarrays to determine the effect of this mutation on gene expression during myeloid and erythroid development of normal human progenitor cells.
ORGANISM(S): Homo sapiens 
2007-10-01 | E-MEXP-583 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of RUNX1-RUNX1T1(9a) transformed mouse bone marrow cells
Single-cell RNA sequencing analysis of RUNX1-RUNX1T1(9a) transformed c-kit positive cells with (Kat2a WT) and without Kat2a (Kat2a NULL). Lineage negative bone marrow cells were collected from Kat2a fl/fl Mx1-Cre-/- and Kat2a fl/fl Mx1-Cre +/- animals after pIpC treatment and transduced with RUNX1-...
ORGANISM(S): Mus musculus 
2022-08-24 | E-MTAB-10853 | biostudies-arrayexpress
GenomicsRUNX1T1 roles in neuroendocrine prostate cancer
RUNX1T1 roles in neuroendocrine prostate cancer
PRJNA1463046 | ENA
UnknownCharacterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
Not available
S-EPMC5983735 | biostudies-literature
TranscriptomicsRUNX1T1 roles in neuroendocrine prostate cancer
Prostate cancer is the second most common cancer in men worldwide, affecting large proportions of the population. Although indolent as prostate adenocarcinoma (PRAD) at first, the standard hormonal therapy inevitably induced metastatic and lethal neuroendocrine prostate cancer (NEPC) or small cell n...
ORGANISM(S): Homo sapiens 
2026-09-16 | GSE330171 | GEO
GenomicsExpanding the transcriptomic sequence space in leukaemia by RUNX1/RUNX1T1-mediated alternative splicing
Expanding the transcriptomic sequence space in leukaemia by RUNX1/RUNX1T1-mediated alternative splicing
PRJNA674515 | ENA
GenomicsThe transcriptional co-repressor Runx1t1 is essential for N-Myc-driven neuroblastoma tumorigenesis [ChIP-Seq]
The transcriptional co-repressor Runx1t1 is essential for N-Myc-driven neuroblastoma tumorigenesis [ChIP-Seq]
PRJNA958158 | ENA
UnknownThe transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis.
Not available
S-EPMC11239676 | biostudies-literature
UnknownEndothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression.
Not available
S-EPMC5481149 | biostudies-literature
Sort   by:  
 Page size