Sort   by:  
 Page size 
ProteomicsDDX3Y and other Male Specific Region of Y Chromosome Genes may modulate neuronal differentiation and mediate various biological pathways in addition to their well described role regulating spermatogenesis
Human tissue based proteomics projects are challenging due to low abundance of proteins and tissue specificity of protein expression. In this study, we aimed to develop a cell-based approach to profile the male specific region of the Y chromosome (MSY) proteins. First, we profiled the expression of ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083949 | MassIVE
ProteomicsProteome Analysis of Human Embryonic Stem Cells Organelles
Here, we have utilized a sub-cellular proteomics approach to analyze the localization of proteins in the nucleus, mitochondria, crude membrane, cytoplasm, heavy and light microsomes. Out of 2002 reproducibly identified proteins, we detected 762 proteins in a single organelle whereas 160 proteins wer...
ORGANISM(S): Homo sapiens (Human) 
2017-04-26 | PXD006271 | Pride
Human embryonic stem cells Organelles 
ProteomicsThe Dynamic Proteome of Oligodendrocyte Lineage Differentiation Features Planar Cell Polarity and Macroautophagy Pathways
Generation of oligodendrocytes (OLs) is a sophisticated multistep process, mechanistic underpinnings of which are not fully understood and demand further investigation. To systematically profile proteome dynamics during human embryonic stem cell (hESC) differentiation into OLs, we applied in-depth q...
ORGANISM(S): Homo sapiens (Human) 
2020-09-16 | PXD017649 | Pride
Human embryonic stem cell  neural stem cell  progenitor cell  oligodendrocyte  wnt signaling  autophagy  quantitative proteomics  multiplexed tandem mass tag 
ProteomicsManiupulating root water supply elicits major shifts in the shoot proteome
Detailed information: Rice (*Oryza sativa* L. cv. Nipponbare) is a drought-susceptible species which is well suited for studies of abiotic stress response because of the comprehensive bioinformatics resource available. By withholding water from the entire root system of young rice plants, or half th...
ORGANISM(S): Oryza sativa (Rice) 
2020-01-22 | PXD000319 | Pride
Split-root Drought Rice Shotgun proteomics 
ProteomicsDDX3Y and other Male Specific Region of Y Chromosome Genes may modulate neuronal differentiation and mediate various biological pathways in addition to their well described role regulating spermatogenesis
Human tissue based proteomics projects are challenging due to low abundance of proteins and tissue specificity of protein expression. In this study, we aimed to develop a cell-based approach to profile the male specific region of the Y chromosome (MSY) proteins. First, we profiled the expression of ...
ORGANISM(S): Homo sapiens (Human) 
2015-09-17 | PXD002428 | Pride
Rna metabolism. Chromosome centric human proteome project (c-hpp) Ddx3y Apoptosis Cell-based human proteome project Cell cycle Shotgun proteomics Y-linked genes 
ProteomicsCharacterizations of molecularly distinct subpopulations of conditioned medium derived extracellular vesicles prior to be used as medicinal product
Mesenchymal stromal cells (MSCs) derived EVs are greatly studied in disease models but lack of manifested characterization rather than generic EVs characterization in different EV subpopulations, greatly limits our ability to bring the most reliable EV types into our studies. We provide a comparativ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD022174 | Pride
Extracellular vesicles Mesenchymal stromal cells Subpopulations 
ProteomicsEnrichment, proteome analysis and transplantation of human embryonic stem cell derived dopaminergic progenitors expressing LMX1a
Despite the progress in safety and efficacy of cell therapy with pluripotent stem cells (PSCs), the presence of residual undifferentiated stem cells or proliferating neural progenitor cells (NPCs) with rostral identity has remained a major challenge. Here we reported the generation of an LMX1A knock...
ORGANISM(S): Homo sapiens (Human) 
2018-06-06 | PXD007837 | Pride
Parkinson disease Pluripotent stem cells Quantitative proteomics Hesc 
ProteomicsMining Missing Protein Landscape in Subcellular Proteome of Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) have capacity of self-renewal and multi-lineage differentiation into derivatives of three germ layers that are of clinical importance for regeneration medicine. Despite the significant progress of hESCs study for clinical application, factors responsible for mainta...
ORGANISM(S): Homo Sapiens (human) 
2019-05-20 | PXD009840 | JPOST Repository
Sort   by:  
 Page size