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MetabolomicsC2C12 cell line knock out SCD1 or SCD2

Lipidomic profiling was performed to compare control, SCD1-knockout, and SCD2-knockout C2C12 cells under standard culture conditions. Cell pellets were collected from routinely cultured cells, rapidly frozen, and stored at −80°C prior to lipid extraction and LC–MS/MS analysis. The study aimed to ...

2026-06-23 | MTBLS14693 | MetaboLights
MetabolomicsLipidomic profiling of Scd1- and Scd2-deficient C2C12 cells during brown adipogenic differentiation with oleic acid supplementation
This study investigated the lipidomic remodeling of Scd1- and Scd2-deficient C2C12 cells during brown adipogenic differentiation. Scd1 or Scd2 knockout cells and corresponding control cells were induced to undergo brown adipocyte-like differentiation for 96 h. To evaluate whether exogenous monounsat...
2026-06-23 | MTBLS14692 | MetaboLights
MetabolomicsPhospholipid profiling of Scd1-defective mice
Not available
ORGANISM(S): Mus musculus 
ST001741 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of livers of stearoyl-CoA desaturase 1-deficient mice to search for gene expression changes unique to SCD1-/- mice on a very low-fat, high- carbohydrate diet.
Stearoyl-CoA desaturase 1-deficient (SCD1-/-) mice have impaired monounsaturated fatty acid (MUFA) synthesis. When maintained on a very low-fat, high-carbohydrate (VLF-HC) diet, SCD1-/- mice develop severe hypercholesterolemia characterized by an increase in apolipoprotein B-containing lipoproteins...
ORGANISM(S): Mus musculus 
2007-11-01 | E-GEOD-3889 | biostudies-arrayexpress
TranscriptomicsExpression data of A939572 SCD1 inhibitor treated ccRCC cells
Presently, there is a deficiency of effective therapies designed to target clear cell renal cell carcinoma (ccRCC), with poor prognosis resulting in patients with advanced disease. Additionally, there is a lack of molecular factors which can be remedially targeted resulting in tumor specific inhibit...
ORGANISM(S): Homo sapiens 
2012-10-11 | E-GEOD-41485 | biostudies-arrayexpress
GenomicsEscherichia coli SCD1
Escherichia coli SCD1 Genome sequencing and assembly
PRJNA205120 | ENA
TranscriptomicsMurine skin gene expression analysis of skin-specific Scd1-deficient and control mice
To help elucidate the metabolic changes in the skin that contribute to the obesity resistance and skin pathology in mice lacking Scd1, we performed microarray analysis of skin gene expression in male skin Scd1 knockout (SKO) and Scd1 flox/flox control (Lox) mice fed a standard rodent diet. We identi...
ORGANISM(S): Mus musculus 
2011-05-09 | E-GEOD-24243 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of livers from SCD1 knockout and wild type mice to elucidate the molecular basis of protection against adiposity in mice lacking of stearoyl-CoA desaturase-1 function
Stearoyl-CoA desaturase (SCD) is a central lipogenic enzyme catalyzing the synthesis of monounsaturated fatty acids, mainly oleate (C18:1) and palmitoleate (C16:1), which are components of membrane phospholipids, triglycerides, wax esters, and cholesterol esters. Several SCD isoforms (SCD1-3) exist ...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2926 | biostudies-arrayexpress
ProteomicsRNF128 aggravates metabolic dysfunction-associated steatotic liver disease progression via stabilization of SCD1
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) progresses from simple steatosis to metabolic dysfunction–associated steatohepatitis (MASH), yet its therapeutic development has been hampered by pathological complexity and heterogeneity. Methods: Bulk RNA-seq and diet-in...
ORGANISM(S): Mus Musculus 
2026-04-10 | PXD076845 |
GenomicsSCD1 Modulates the Skin Homeostasis via Sustaining Hemidesmosomes
SCD1 Modulates the Skin Homeostasis via Sustaining Hemidesmosomes
PRJNA764193 | ENA
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