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MDA-MB-231-luc2 cells were treated with the PPARd specific agonist GW501516 and the resulting expression changes profiled.
ORGANISM(S): Homo_sapiens 
MDA-MB-231luc1 cells were treated for 6h with PPARbd specific agonists, antagonists and control substances. In addition the influence of PPARbd on gene expression was analyzed via siRNA mediated PPARbd depletion.
ORGANISM(S): Homo sapiens 
Protein methyltransferases (PMTs) comprise a major class of epigenetic regulatory enzymes with therapeutic relevance. Here we present a collection of chemical probes and associated reagents and data to elucidate the function of human and murine PMTs in cellular studies. Our collection provides inhib...
ORGANISM(S): Homo sapiens (Human) 
2018-12-19 | PXD009028 | Pride
The human general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is thought to nucleate RNA polymerase II (Pol II) preinitiation complex formation on all protein coding gene promoters and thus, be crucial for ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD028352 | Pride
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