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MetabolomicsMetabolic responses of rice cultivars with different tolerance to combined heat and drought stress under field conditions
Rice is susceptible to both heat and drought stress, in particular during flowering and grain filling, when both grain yield and quality may be severely compromised. However, under field conditions, these two stresses rarely occur separately. Under well-watered conditions, plants avoid heat stress b...
2019-04-25 | MTBLS801 | MetaboLights
ProteomicsQuantitative analysis of murine T-cells
1D-LC-MS/MS analysis of OGE-prefractionated and TMT labeled mouse samples consiting of 2 unstimulated and 2 stimulated T-cell samples. The acquired raw-files were converted to the mascot generic file (mgf) format using the msconvert tool (part of ProteoWizard, version 3.0.4624 (2013-6-3)). Using the...
ORGANISM(S): Mus musculus (Mouse) 
2014-12-02 | PXD000543 | Pride
T-cells Quantitative analysis Tmt labeling Mouse 
TranscriptomicsThe systematic shortening of 3’ UTRs has limited influence on the relative change in protein abundance in proliferating cells
Alternative polyadenylation is an important cellular mechanism that enables generation of mRNA isoforms that differ in their 3' untranslated regions (3' UTRs) and consequently in their susceptibility to miRNA and RNA binding protein mediated regulation. A dramatic change in polyadenylation site usa...
ORGANISM(S): Homo sapiens 
2014-09-25 | E-GEOD-54950 | biostudies-arrayexpress
GenomicsChIP-seq analysis of histone modifications and RNA polymerase II at 4 stages of directed cardiac differentiation of mouse embryonic stem cells
We interrogated the genome-wide occupancy of histone modifications and RNA polymerase II at several stages of an mouse embryonic stem cell to cardiomyocyte directed differentiation protocol. These four stages represent timepoints when differentiating cultures are enriched for embryonic stem cells (...
ORGANISM(S): Mus musculus 
2013-06-15 | E-GEOD-47949 | biostudies-arrayexpress
TranscriptomicsDynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-06-15 | E-GEOD-47950 | biostudies-arrayexpress
UnknownMolecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels.
Not available
S-EPMC8394053 | biostudies-literature
UnknownComparison of Hydrogels for the Development of Well-Defined 3D Cancer Models of Breast Cancer and Melanoma.
Not available
S-EPMC7465483 | biostudies-literature
ProteomicsLoss of function variants in SAXO6, encoding a microtubule inner protein of photoreceptor cilia, causes a late-onset retinal dystrophy
Over 500 genes have been linked to various forms of inherited retinal diseases (IRDs), a class of Mendelian conditions affecting the survival and function of rod and cone photoreceptors and leading in most instances to progressive visual loss. Yet, some patients still lack a clear genetic diagnosis,...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2026-01-28 | MSV000100624 | MassIVE
ProteomicsMurine colon HUNTER N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060854 | Pride
Legumain Mouse Colon Colitis Hunter 
ProteomicsNaive and DSS Murine Colon TMTpro bRP fractionation N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060852 | Pride
Mouse Protease Fractionation Legumain N-terminomics Colon Colitis 
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