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RNA-seq is a sensitive and accurate technique to compare steady state levels of RNA between different cellular states. However, as it does not provide an account of transcriptional activity per se, other technologies are needed to more precisely determine acute transcriptional responses. Here, we ha...
ORGANISM(S): Homo sapiens 
In this study, the proteome and metabolic properties of primary subcutaneous (s) and visceral (v) adipose tissue-derived stromal stem cells (ASC) from old and young rabbits were analysed by a mass spectrometry-based label-free quantification approach and combined with metabolic mitochondrial respira...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2025-01-19 | PXD057467 | Pride
Krohn2011 - Cerebral amyloid-β proteostasis regulated by membrane transport protein ABCC1 This model is described in the article: Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice. Krohn M, Lange C, Hofrichter J, Scheffler K, Stenze...
2024-09-02 | BIOMD0000000618 | BioModels
SAGE profile of the rat superior olivary complex (SOC). Rats were 60 days old (P60). Keywords: other
ORGANISM(S): Rattus norvegicus 
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 

We conducted whole-genome sequencing of probands from several melanoma families, identifying one individual carrying a novel germline variant (c.G1075A, NM_000248.3; p.E318K, NP_000239.1; rs149617956) in the melanoma lineage-specific oncogene MITF. While the variant cosegregated with melanoma in ...

In order to identify differentially abundant proteins, human plasma samples from COVID-19 patients with either a mild or moderate (MM) or a critical or severe (CS) disease course from acute phase of infection were analyzed on antibody microarrays 998 different proteins by 1,425 antibodies.
ORGANISM(S): Homo sapiens 
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