Sort   by:  
 Page size 
MetabolomicsComparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay)
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases. Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can also be internalized by host cells and persist within these cells. In the present study, we comparatively analyzed survival an...
2015-07-01 | MTBLS102 | MetaboLights
UnknownOtotoxicity in children with high-risk neuroblastoma: prevalence, risk factors, and concordance of grading scales--a report from the Children's Oncology Group.
Not available
S-EPMC3918536 | biostudies-literature
ProteomicsAnalysis of secreted S. aureus proteins after isolation of phagosomes from infected human epithelial cells
Bacteria such as Staphylococcus aureus are generally engulfed by the host with a membrane when internalized by non-professional phagocytic host cells. These vacuoles then mature to phagosomes which can fuse with lysosomes enabling killing and digestion of the pathogen. Former proteome approaches enr...
ORGANISM(S): Homo sapiens (Human) Staphylococcus aureus 
2018-06-29 | PXD007885 | Pride
Host-pathogen-interaction Phagosomes Staphylococcus aureus Quantitative proteomics Single reaction monitoring (srm) Virulence factors 
ProteomicsShotgun proteomic analysis of Bordetella pertussis response to iron availability
B. pertussis Tohama I was cultivated in iron-depleted or iron-repleted medium in order to monitor proteins which are influence by iron supply. More than 200 proteins displayed increased or decreased levels. Proteins involved in iron acquisition, biofilm production and oxidative stress response were ...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2015-03-16 | PXD001280 | Pride
Shotgun proteomics Iron limitation B. pertussis 
ProteomicsProteome analysis of Bordetella pertussis isolated from human macrophages
Previous studies indicated that B. pertussis, historically considered as extracellular pathogen, can invade and replicate within human macrophages. In order to investigate factors involved in the intracellular survival, we analyzed the proteome of intracellular B. pertussis at 3h and 48 h post macro...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2016-02-29 | PXD002997 | Pride
Proteomics Macrophages B. pertussis Internalization 
ProteomicsSynergistic potential of sulfated hyaluronic acid and dexamethasone
Both sulfated hyaluronic acid and dexamethasone are candidates for the functionalization of bone grafts as they were shown to enhance the differentiation of osteoblasts from bone marrow stromal cells in vitro and in vivo. However, the underlying mechanisms are not fully understood. Furthermore, stud...
ORGANISM(S): Homo sapiens (Human) 
2019-03-15 | PXD009434 | Pride
Human Hbmsc Lc-msms Sulfated hyluronic acid Osteoblasts Dexamethasone 
OtherShotgun proteome analysis of Bordetella pertussis reveals a distinct influence of iron availability on the bacterial metabolism, virulence, and defense response.
Data from ProteomeXchange, PXD ID: PXD001280. File: 120313_O4_YL__Bp_Fe_1.mzml. Published as part of Proteomics. 2015 Mar 9 . From the Abstract: {{i}} One of the mechanisms involved in host immunity is the limitation of iron accessibility to pathogens, which in turn provokes the corresponding physi...
ORGANISM(S): Bordetella_pertussis_tohama_i 
GPM32310018525 | GPMDB
Resource Reanalysis 
ProteomicsProteomic characterization of calcium macrophages
In this study, macrophages, which differentiated from monocytes due to exposure to calcium and no further growth factors, were characterized. For this purpose, their proteomic profile was compared to monocytes, M1 macrophages, M2 macrophages, DCs, and foam cells obtained from healthy donors or patie...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026888 | Pride
Human Macrophages Calcium Rheumatoid arthritis 
ProteomicsHfq is involved in global protein expression and stress response in Bordetella pertussis
In this study, we used gel-free nanoLC-MS/MS-based proteomics to compare the protein profile of B. pertussis wild type and an isogenic hfq defective mutant strain under control an iron limited conditions. We found that Hfq affects the abundance of 302 proteins, which represents 8% of the total B. pe...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2020-02-18 | PXD011753 | Pride
Proteomics Iron limitation Stress response Hfq B. pertussis 
ProteomicsA global Staphylococcus aureus proteome resource applied to the in vivo characterization of host- pathogen interactions
1. DDA dataset used for Staphylococcus aureus HG001 PeptideAtlas build (https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=435) 2. DIA and DDA dataset for the quantitative analyses of the publication (in the update section)
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 (ncbitaxon:93061) Homo Sapiens (ncbitaxon:9606) 
2018-06-21 | MSV000082483 | MassIVE
Sort   by:  
 Page size