Sort   by:  
 Page size 
ProteomicsDisassembly of Functional Membrane Microdomains Relapses Antibiotic Resistance in Staphylococcus aureus
Bacteria spatially confine cellular processes like protease secretion and signal transduction in membrane platforms termed functional membrane microdomains, which in certain organisational and functional features resemble the lipid rafts of eukaryotic cells. However, a rigorous understanding of thei...
ORGANISM(S): Staphylococcus aureus 
2019-01-08 | PXD006546 | Pride
Drm Dsm Membrane platforms Staphylococcus aureus Lc-ms/ms 
ProteomicsThe 3’-UTR of MYC couples RNA polymerase II function to ribonucleotide levels
Deregulated expression of MYC enhances glutamine utilization and renders cell survival dependent on glutamine, inducing “glutamine addiction”. Surprisingly, colon cancer cells that express high levels of MYC due to WNT pathway mutations, are not glutamine-addicted but undergo a reversible cell cycle...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD005829 | Pride
Myc Mrna-protein interaction Glutamine Nanolc-ms/ms 
ProteomicsChinese hamster ovary (CHO) cell Surfaceome LC-MSMS and mRNA expression analysis
The production of biopharmaceuticals relies on robust cell systems that can produce recombinant proteins at high levels, and grow and survive in the stressful bioprocess environment. Chinese hamster ovary cells (CHO) as the main production hosts offer a variety of advantages including robust growth ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2022-10-15 | PXD033581 | Pride
Lc-msms Signaling pathways Mrna expression Cho cells Surfaceome 
GenomicsSCLC_SNP_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000558 | EGA
Genomicsena-DATASET-RTL-11-03-2015-12:07:49:303-16 - samples
Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...
EGAD00001001273 | EGA
Genomicsena-DATASET-RTL-06-02-2015-14:59:15:066-180 - samples
RNA-sequencing (RNA-seq) was performed with RNA extracted from fresh-frozen human tumor tissue samples. cDNA libraries were prepared from poly-A selected RNA applying the Illumina TruSeq protocol for mRNA. The libraries were then sequenced with a 2 x 100bp paired-end protocol to a minimum mean cover...
EGAD00001001244 | EGA
GenomicsComprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
EGAS00001000925 | EGA
GenomicsDAC University of Cologne
Data Access Committee EGAC00001000064
EGAC00001000064 | EGA
UnknownPerformance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia.
Not available
S-EPMC9877422 | biostudies-literature
UnknownX-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Not available
S-EPMC8532080 | biostudies-literature
Sort   by:  
 Page size