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ProteomicsTWIST1 expression is associated with high-risk Neuroblastoma and promotes Primary and Metastatic Tumor Growth
In this study, merging in silico transcriptomic data and in situ TMA studies, we first highlighted the clinical significance and the value as prognostic factors of the embryonic TFs TWIST1 and TWIST2, thus linking their level of expression with the outcome of NB patients. Secondly, using NB cells k...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD024200 | Pride
Neuroblastoma Myofibroblasts Twist1/2 Tumor-stroma cross-talk Metastasis Tumor microenvironment Secretome Extracellular matrix 
UnknownAPC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures.
Not available
S-EPMC6492969 | biostudies-literature
GenomicsEGAS00001002091 - samples
Using sequencing and gene expression analyses, we identified a subgroup of HCA characterized by fusion of the INHBE and GLI1 genes and activation of sonic hedgehog pathway. Molecular subtypes of HCAs associated with different patients’ risk factors for HCA, disease progression, and pathology feature...
EGAD00001003092 | EGA
GenomicsA new subgroup of hepatocellular adenomas with sonic hedgehog pathway activation
Hepatocellular adenomas (HCA) are benign liver tumors divided in molecular subtypes characterized by mutations inactivating HNF1A, activating β-catenin or the IL-6/JAK/STAT inflammatory pathway. Molecular analyses of 533 HCA developed in 411 patients identified a new tumor subgroup with Sonic Hedgeh...
EGAS00001002091 | EGA
UnknownOncogenic Fusions May Be Frequently Present at Resistance of EGFR Tyrosine Kinase Inhibitors in Patients With NSCLC: A Brief Report.
Not available
S-EPMC8474286 | biostudies-literature
UnknownVariants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer.
Not available
S-EPMC3221775 | biostudies-literature
UnknownThe genomic and transcriptomic landscape of metastastic urothelial cancer.
Not available
S-EPMC11452614 | biostudies-literature
UnknownDeciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development.
Not available
S-EPMC11451117 | biostudies-literature
UnknownNeuropilin-1 cooperates with PD-1 in CD8+ T cells predicting outcomes in melanoma patients treated with anti-PD1.
Not available
S-EPMC9301874 | biostudies-literature
UnknownA simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer.
Not available
S-EPMC4546456 | biostudies-literature
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