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Similar to the bone marrow, the mammary gland contains a distinct population of Hoechst-effluxing side population cells, MG-SPs. To better characterize MG-SPs, their microarray gene profiles were compared to the remaining cells, which retain Hoechst dye (MG-NSPs). For analysis, gene ontology (GO) t...
ORGANISM(S): Mus musculus 
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
Due to its antimicrobial activity, silver nanoparticles (Ag-NPs) are among the most used NPs worldwide, yet little information is available regarding their effects, particularly in soil dwelling organisms. Enchytraeids (Oligochaeta) are important members of the soil fauna which actively contribute t...
ORGANISM(S): Enchytraeus albidus 
TREM-1 is an orphan immunoreceptor expressed on monocytes, macrophages, and neutrophils. TREM-1 associates with and signals via the adapter protein DAP12/TYROBP, which contains an immunoreceptor tyrosine-based activation motif (ITAM). TREM-1 activation by receptor cross-linking is pro-inflammatory, ...
ORGANISM(S): Homo sapiens 
This study was initiated to characterize early DOX-induced changes in cardiac gene expression in order to identify potential additional areas for clinical intervention. Male spontaneously hypertensive rats (SHR) received 3 mg/kg DOX or vehicle (iv) 30 minutes following pretreatment with 50 mg/kg DZ...
ORGANISM(S): Rattus norvegicus 
Statins lower plasma cholesterol by as much as 50%, thus reducing future cardiovascular events. However, the physiological effects of statins are diverse and not all are related to LDL-C lowering. We performed a small clinical pilot study to assess the impact of statins on lipoprotein-associated pro...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002633 | Pride
The physiological basis of the hypothesis that temperature is the primary governing factor of bacterial cell inactivation under otherwise non-growth permissive conditions was investigated. Application of simultaneous low pH (pH 3.5) and low water activity (aw = 0.9; 2.5 M NaCl) conditions, applied t...
ORGANISM(S): Listeria monocytogenes 
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