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ProteomicsProteomics of boar seminal plasma extracellular vesicles
This project comprises 12 proteomic samples analyzed using data-independent acquisition (DIA, also known as SWATH). Proteins were isolated from extracellular vesicles enriched from the seminal plasma of boar AI semen doses, including samples from high-fertility males (n = 6) and reduced-fertility ma...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-06-10 | PXD079300 | Pride
Proteomics of boar seminal plasma extracellular vesicles 
ProteomicsPig,Seminal plasma extracellular vesicles,LC-MS
We performed proteomics analysis of Yorkshire Seminal plasma extracellular vesicles(SPEVs) with high or low sperm motility to investigate specific biomarker affecting sperm motility.Twelve Yorkshire boars with extremely high (H) or low (L) sperm motility were selected, with six individuals in each g...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-06 | PXD050238 | Pride
Lc-ms Seminal plasma extracellular vesicles Pig 
ProteomicsCharacterization of extracellular vesicles in human seminal plasma: a multiomic analysis
Extracellular Vesicles (EVs) derived from seminal plasma have achieved considerable attention due to their potential role in male reproductive physiology and pathology. In this study, we employed a comprehensive proteomic and transcriptomic approach to investigate the molecular signatures of EVs iso...
ORGANISM(S): Homo sapiens (Human) 
2025-06-30 | PXD051361 | Pride
Extracellular vesicles  seminal plasma  multi-omics  proteomics  transcriptomics 
ProteomicsPig,extracellular vesicles,LC-MS
Seminal plasma contains a large number of extracellular vesicles (EVs). However, the roles of these EVs and their interactions with sperm are not clear. To identify the important molecules affecting sperm motility in EVs, we performed proteomics analysis of SPEVs from the two groups with different s...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-11-04 | PXD027541 | Pride
Seminal plasma Lc-ms Extracellular vesicles Pig 
ProteomicsCharacterization of extracellular vesicles in human seminal plasma: a multiomic analysis
Extracellular Vesicles (EVs) derived from seminal plasma have achieved considerable attention due to their potential role in male reproductive physiology and pathology. In this study, we employed a comprehensive proteomic and transcriptomic approach to investigate the molecular signatures of EVs iso...
ORGANISM(S): Homo sapiens (Human) 
2025-06-30 | PXD051390 | Pride
Extracellular vesicles  seminal plasma  multi-omics  proteomics  transcriptomics 
ProteomicsQuantitative proteomic analysis of seminal plasma, sperm membrane proteins and seminal extracellular vesicles suggests vesicular mechanisms aid in the removal and addition of proteins to the ram sperm membrane.
Quantitative proteomic studies are contributing greatly to our understanding of the spermatozoon through the provision of detailed information on the proteins spermatozoa acquire and shed in the acquisition of fertility. Extracellular vesicles (EVs) are thought to aid in the delivery of proteins to ...
ORGANISM(S): Ovis aries 
2020-05-08 | PXD017537 | Pride
Prostasomes Microvesicles Edil3 Epididysomes Sperm surface 
ProteomicsTMT-based proteomics and phosphoproteomics analysis of proteome changes in seminal plasma extracellular vesicles of azoospermia
The proteome and phosphoproteomics changes were quantified in seminal plasma extracellular vesicles among healthy individuals with normal sperm, nonobstructive azoospermia and obstructive azoospermia using TMT 10-plex by LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022843 | Pride
Tmt  azoospermia  extracellular vesicles  seminal plasma  proteomics 
ProteomicsProteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomark
Predicting male fertility remains a major challenge in livestock industry. Seminal plasma contains a heterogeneous population of extracellular vesicles (sEVs) that are involved in the regulation of sperm functionality and may therefore be involved in male fertility. The aim of this study was to eval...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-02-02 | PXD055970 | Pride
Pig  seminal plasma  extracellular vesicles  proteomics  diapasef 
ProteomicsThe proteome of large or small extracellular vesicles in pig seminal plasma differs and defines sources and biological functions. Spectral Library
Seminal plasma contains many and morphologically heterogeneous extracellular vesicles (sEVs) which, released by cells of the testis, epididymis and accessory sex glands, are involved in male and female reproductive processes. The goal of this study was to describe the proteome of porcine sEVs isolat...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-02-15 | PXD039833 | Pride
Seminal plasma Proteomics Subsets Extracellular vesicles 
GenomicsThe whole transcriptome analysis for seminal plasma extracellular vesicles (SPEVs) of Yorkshire boars
The seminal plasma contains large quantities of extracellular vesicles (EVs). However, the role of these EVs and their interactions with sperms are not clear. To identify the important molecules affecting sperm motility in EVs, we sequenced the EVs in the seminal plasma of Yorkshire boars with diffe...
ORGANISM(S): Sus scrofa 
2023-01-04 | GSE216966 | GEO
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