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TranscriptomicsGenome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila
Chromatin insulators are functionally conserved DNA-protein complexes that are situated throughout the genome and organize independent transcriptional domains.  Previous work implicated RNA as an important cofactor in chromatin insulator activity, although the mechanisms by which RNA affects insulat...
ORGANISM(S): Drosophila melanogaster 
2013-01-29 | E-GEOD-41950 | biostudies-arrayexpress
TranscriptomicsMicroRNA profile of exosome from serum samples of Kawasaki disease
To further development of our miRNA diagnostic approach to Kawasaki disease(KD), we have employed microRNA microarray expression profiling as a discovery platform to identify microRNAs as the potential biomarkers to rapidly diagnose Kawasaki disease. Pooled exosome of serum in equal amount from 5 he...
ORGANISM(S): Homo sapiens 
2014-09-03 | E-GEOD-60965 | biostudies-arrayexpress
GenomicsMurine cells: MSC+LLC-serum-exosome vs LLC-serum-exosome
Murine cells: MSC+LLC-serum-exosome vs LLC-serum-exosome
PRJNA490558 | ENA
ProteomicsMouse serum exosome proteomics
This project was focused to compare the different protein profile of serum exosome from normal mice and diabetic mice.
ORGANISM(S): Mus musculus (Mouse) 
2018-07-03 | PXD009221 | Pride
Proteomics Serum exosome 
TranscriptomicsMicroRNA sequencing of human serum exosomes from women with different age and hormonal status
This study investigated differences in serum exosome microRNA-cargo, obtained from healthy postmenopausal monozygotic twins (n=10 pairs), from which the other sister was using estrogen-based hormone replacement therapy (HRT) and the other was not under treatment. In addition, premenopausal women (n=...
ORGANISM(S): Homo sapiens 
2017-02-14 | E-MTAB-5245 | biostudies-arrayexpress
ProteomicsRat Serum Exosome LC-MSMS(Label free)
LC-MSMS (Label free) was performed to find differential proteins in maternal rat serum exosome between 3 normal pregnant rats and 3 pregnant rats carrying fetuses with spina bifida aperta induced by all-trans retinoic acid (Sigma; 4% [wt/vol] in olive oil; 140 mg/kg body weight by gavage) at pregnan...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-14 | PXD023775 | Pride
Serum exosome Lc-msms Label free Rat 
TranscriptomicsHP1, H3-K27me3, and H3-K9me3 Cut & Tag of Het (Cbx1+/+, Cbx3+/+, Cbx5+/-) and TKO (Cbx1-/-, Cbx3-/-, Cbx5-/-) bipotential mouse embryonic liver (BMEL) cells
Cut & Tag was used to localize the 3 mouse HP1 proteins (Cbx1,Cbx3,Cbx5) to the genome of BMEL (bipotential mouse embryonic liver) cells. Het BMEL cells are Cbx1+/+, Cbx3+/+, Cbx5+/- HP1-TKO (triple knock-out cells) are Cbx1-/-, Cbx3-/-, Cbx5-/-. The HP1_TKO cells were used to verify the specificity...
ORGANISM(S): Mus musculus 
2025-06-14 | E-MTAB-15189 | biostudies-arrayexpress
GenomicsThe RNA Exosome Promotes Transcription Termination of backtracked RNA Polymerase II
Large fractions of genomes are expressed in most eukaryotic cells, generating a diverse repertoire of protein-coding and non-coding transcripts. With such complexity, and as the number of mRNA molecules per cell are often low, it is clear that errors anywhere in the gene expression process could hav...
ORGANISM(S): Schizosaccharomyces pombe 
2014-09-20 | E-MTAB-2237 | biostudies-arrayexpress
GenomicsSerum exosome microRNAs predict multiple sclerosis disease activity after fingolimod treatment
Serum exosome microRNAs predict multiple sclerosis disease activity after fingolimod treatment
PRJNA588268 | ENA
ProteomicsMagnetic Transferrin Assay (MTA) as a novel approach for discovering serum exosome derived protein biomarkers in neurological diseases
We developed TF-based MNPs (TF-MNPs) to isolate blood-derived exosome in this study and isolated the blood-derived exosomes of patients with neuroinflammatory diseases, such as dementia, Parkinson’s disease and multiple sclerosis via this strategy and then evaluated the proteomic profiling of these ...
ORGANISM(S): Homo sapiens (Human) 
2023-02-20 | PXD038555 | Pride
Human Serum exosome Lc-msms Dementia Multiple sclerosis Parkinson Neurological disease 
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