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ProteomicsCombined cysteine oxidation (C6-CPT/CysPAT) proteomics and phosphoproteomics of pervanadate-treated of HEK293T cells
HEK293T cells were treated with pervanadate for 0, 5 or 15 minutes to evaluate the effects on the phosphorylation and cysteine oxidation status across the proteome. Samples were labelled withTMT 18plex and C6-CPT/CysPAT labelling was used to allow the simultaneous enrichment of both the phosphoprote...
ORGANISM(S): Homo sapiens (Human) 
2026-06-22 | PXD059503 | Pride
Hek293t Cysteine C6-cyspat C6-cpt Redox Phosphoproteomics Pervanadate 
ProteomicsQuantitative tyrosine phosphoproteomics of wild type and PTPRK KO tumour xenografts
TMT-based quantitation of tyrosine phosphoproteomes of wild type and PTPRK KO tumour xenografts to determine additional mechanisms of tumour suppression by receptor tyrosine phosphatase PTPRK
ORGANISM(S): Homo sapiens (Human) 
2024-07-03 | PXD050617 | Pride
Tmt Phosphatase Ptprk Tyrosine phosphoproteomics Tumour xenografts 
ProteomicsThe homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion
Cell-cell communication in multicellular organisms depends on the dynamic and reversible phosphorylation of protein tyrosine residues. The receptor-linked protein tyrosine phosphatases (RPTPs) receive cues from the extracellular environment and are well placed to influence cell signaling. However, t...
ORGANISM(S): Homo sapiens (Human) 
2019-03-29 | PXD013055 | Pride
Phosphorylation  silac 
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