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TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
ProteomicsCyclosporine A Modulates LSP1 Protein Levels in Human B Cells to Attenuate B Cell Migration at Low O2 Levels
Coordinated migration of B cells within and between secondary lymphoid tissues is required for robust antibody responses to infection or vaccination. Secondary lymphoid tissues normally expose B cells to a low O2 (hypoxic) environment. Recently, we have shown that human B cell migration is modulated...
ORGANISM(S): Homo sapiens (Human) 
2022-08-24 | PXD036167 | Pride
Chemotaxis Cxcr4 Human b cells Lsp1 
GenomicsDNA Cytosine Hydroxymethylation Levels Are Distinct Among Peripheral Blood Leukocytes
Peripheral blood leukocytes are the most commonly used surrogates to study epigenome-induced risk and epigenomic response to disease related stress. We considered the hypothesis that the TET enzyme catalyzed hydroxymethylation of 5mC to 5hmC might vary among peripheral blood leukocytes and reflect t...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-70519 | biostudies-arrayexpress
UnknownThe complete mitochondrial genome sequence and annotation of Tylopilus plumbeoviolaceoides T.H. Li, B. Song & Y.H. Shen, 2002 (Boletaceae, Boletoideae).
Not available
S-EPMC9225691 | biostudies-literature
TranscriptomicsATAC-seq of spleen B cells from B cell-specific Zeb2-CKO and WT mice
To test the differences in chromatin accessibility of spleen B cells between Zeb2-CKO mice and WT mice, we isolated naive B cells from B cell-specific Zeb2-CKO and WT mice and cultured them in ABC-inducing culture for 3 days and performed ATAC assay.
ORGANISM(S): Mus musculus 
2025-05-12 | E-MTAB-12905 | biostudies-arrayexpress
GenomicsHigh density copy number analysis and whole exome sequencing of diffuse large B-cell lymphoma

Diffuse Large B-cell Lymphoma (DLBCL) represents the most common form of B-cell non-Hodgkin Lymphoma (B-NHL), accounting for ~30% of the de-novo diagnoses and also arising as a frequent clinical evolution of Follicular Lymphoma (FL). The molecular pathogenesis of DLBCL is associated with multip...

phs000328.v1.p1 | EGA
ProteomicsSNX10 regulates the proliferation, apoptosis and cell cycle of acute B lymphoblastic leukemia cells via the PI3K/Akt signaling pathway
B-cell acute lymphoblastic leukemia (B-ALL) is a type of acute lymphoblastic leukemia that originates from B cells. It typically occurs in children and adolescents, but it can also appear in adults. Sorting nexin 10 (SNX10) has recently been identified as a significant regulatory factor in various t...
ORGANISM(S): Homo Sapiens 
2025-03-14 | PXD061830 |
TranscriptomicsATAC-seq in naive B cells, CD11c+T-bet+ B cells, CD11c-T-bet- B cells from Bm12-induced lupus T-bet reporter mice
To test the chromatin accessibility of different immune cell subsets, we isolated naive B cells CD11c+T-bet+ B cells, CD11c-T-bet- B cells by flow cytometry from Bm12-induced lupus T-bet reporter mice and performed ATAC assay.
ORGANISM(S): Mus musculus 
2025-05-16 | E-MTAB-12903 | biostudies-arrayexpress
TranscriptomicsRNA-seq data of ABC from Bm12-induced lupus model
Age-associated B cells (ABCs) accumulate in systemic autoimmunity, and contributes to pathogenesis. ABCs are characterized by high expression of CD11c and T-bet. As a transcription factor, T-bet cannot be labeled in live cells with antibodies, so we constructed a reporter mouse strain in which fluor...
ORGANISM(S): Mus musculus 
2023-02-16 | E-MTAB-12568 | biostudies-arrayexpress
ProteomicsEpstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation
Epstein-Barr virus (EBV) causes Burkitt, Hodgkin, and post-transplant B-cell lymphomas. How EBV remodels metabolic pathways to support rapid B-cell outgrowth remains largely unknown. To gain insights, primary human B-cells were profiled by tandem-mass-tag based proteomics at rest and at 9 time point...
ORGANISM(S): Homo sapiens (Human) Epstein-barr virus strain p3hr-1 
2019-06-28 | PXD013034 | Pride
Herpesvirus One-carbon metabolism Epstein-barr virus Host-pathogen interaction Quantitative proteomics Tandem mass tag 
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