G-quadruplexes (G4s) are widely existing stable DNA secondary structures in mammalian cells. A long-standing hypothesis is that timely resolution of G4s is needed for efficient and faithful DNA replication. In vitro, G4s may be unwound by helicases or alternatively resolved via DNA2 nuclease-mediate...
Effect of the high nitrogen insensitive 9 (hni9) mutation in contrasted nitrogen environments. hni9 vs. WT, and Low Nitrogen vs. High Nitrogen environments. 2 biological replicates per genotype/environment.
Human brain organoids are emerging models to study human brain development and pathology as they recapitulate the development and characteristics of major neural cell types, and enable manipulation through an in vitro system. Over the past decade, with the advent of spatial technologies,...
