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UnknownPharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.
Not available
S-EPMC6312637 | biostudies-literature
TranscriptomicsRegulation of extraembryonic endoderm stem cell differentiation by Nodal and EGF-CFC signaling
The signaling pathway for Nodal, a ligand of the transforming growth factor-beta (TGF-beta) superfamily, plays a central role in regulating the maintenance and/or differentiation of stem cell types that can be derived from the peri-implantation mouse embryo. Extraembryonic endoderm stem (XEN) cells ...
ORGANISM(S): Mus musculus 
2011-11-29 | E-GEOD-23675 | biostudies-arrayexpress
ProteomicsLC-MS/MS of conditioned media from vascularized tissue with and without cardiac microtissues.
Geometrically controlled cardiac microtissues promote vascularization and reduce inflammation in vitro and in vivo Cardiac tissue engineering faces challenges due to inadequate vascularization and lack of effective strategies to control inflammation post transplantation. . This study explores the ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD055832 | Pride
Cardiomyocytes Myocardium Organ-on-a-chip Vascularization Immune response Bioprinting Tissue engineering 
MetabolomicsLegume rhizodeposition promotes nitrogen fixation by soil microbiota under crop diversification

Biological nitrogen fixation by free-living bacteria and rhizobial symbiosis with legumes plays a key role in sustainable crop production. Here, we study how different crop combinations influence the interaction between peanut plants and their rhizosphere microbiota via metabolite deposition and ...

2024-03-19 | MTBLS6537 | MetaboLights
TranscriptomicsComparative genomic hybridization of 269 individuals from three geographically distinct human populations to investigate copy number variation
We conducted comparative genome hybridization experiments to catalogue the common copy number variation evident between 269 individuals from three geographically distinct human populations (Yoruban, Chinese/Japanese, European) against a single reference individual.
ORGANISM(S): Homo sapiens 
2006-07-31 | E-TABM-107 | biostudies-arrayexpress
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
TranscriptomicsIdentification of miR-181 target genes and a common prognostic gene signature in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30258 | biostudies-arrayexpress
UnknownCanvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Not available
S-EPMC6311695 | biostudies-literature
MetabolomicsPTER is an N-acetyltaurine hydrolase that regulates feeding and obesity

Taurine is a conditionally essential micronutrient and one of the most abundant amino acids in humans1-3. In endogenous taurine metabolism, dedicated enzymes are involved in biosynthesis of taurine from cysteine as well as the downstream metabolism of secondary taurine metabolites4,5. One such ta...

2024-09-11 | MTBLS10408 | MetaboLights
UnknownSystematic assessment of long-read RNA-seq methods for transcript identification and quantification.
Not available
S-EPMC11543605 | biostudies-literature
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