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TranscriptomicsThe conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells
Different from canonical ubiquitin-like proteins, Hub1 does not form covalent conjugates with substrates but binds proteins non-covalently. In Saccharomyces cerevisiae, Hub1 associates with spliceosomes and mediates alternative splicing of SRC1, without affecting pre-mRNA splicing generally. Human H...
ORGANISM(S): Homo sapiens 
2014-05-30 | E-GEOD-56878 | biostudies-arrayexpress
UnknownID8 cells manifest phenotypic plasticity and molecular heterogeneity of high-grade serous ovarian cancer in response to the local tissue niche.
Not available
S-EPMC12494684 | biostudies-literature
UnknownInnovative study on chalcopyrite flotation efficiency with xanthate and ester collectors blend using response surface methodology (B.B.D): towards sustainability.
Not available
S-EPMC11697008 | biostudies-literature
ProteomicsPre-mRNA splicing function of the ubiquitin-like protein Hub1/UBL-5 in Caenorhabditis elegans
The conserved ubiquitin-like protein Hub1/UBL-5 associates with proteins non-covalently. In yeast and human cells, Hub1 promotes splicing of precursor mRNAs with weak introns and alternative splicing, however, its splicing function has remained elusive in multicellular organisms. We demonstrate the ...
ORGANISM(S): Caenorhabditis elegans 
2024-05-21 | PXD033914 | Pride
Trans-splicing and c. elegans Outron-containing transcripts Spliceosome Pre-mrna splicing 
UnknownDesidustat in Anemia due to Dialysis-Dependent Chronic Kidney Disease: A Phase 3 Study (DREAM-D).
Not available
S-EPMC9254304 | biostudies-literature
UnknownDynamics of a multicomponent vesicle in shear flow.
Not available
S-EPMC5505236 | biostudies-literature
ProteomicsID8 cells manifest phenotypic plasticity and molecular heterogeneity of high-grade serous ovarian cancer in response to the local tissue niche ID8 cells manifest phenotypic plasticity and molecular heterogeneity of high-grade serous ovarian cancer in response to the local tissue niche
Spontaneously transformed mouse ovarian surface epithelial cell line ID8 generates a syngeneic mouse model, frequently used in pre-clinical evaluation. Towards a precise, subtype-specific perspective of such applications, we thought it pertinent to study its stratification into a specific molecular ...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-13 | PXD060359 | Pride
Phenotypic plasticity D8 Ascites. 
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