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ProteomicsGeneration of fibronectin fragments by pancreatic trypsin: a physiological mechanism hampering PDAC progression.
In this study we demonstrate that spheroids isolated from normal pancreas and co-trasplanted with PDAC orthotopically in mouse pancreas , inhibited tumor growth. Fibronectin proteolytic fragments generated by trypsin and released by pancreatic spheroids, were responsible for of the observed effect. ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035770 | Pride
Pdac Trypsin Fibronectin Fgfr Fak 
UnknownIdentification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming.
Not available
S-EPMC8459394 | biostudies-literature
TranscriptomicsRegulation of Vertebrate Nervous System-Specific Alternative Splicing and Development by an SR-Related Protein
Alternative splicing is a key process underlying the evolution of increased proteomic and functional complexity and is especially prevalent in the mammalian nervous system. However, the factors and mechanisms governing nervous system-specific alternative splicing are not well understood. Through a g...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-16187 | biostudies-arrayexpress
TranscriptomicsTranscriptome Sequencing During Mouse Brain Development Identifies Long Non-Coding RNAs Functionally Involved in Neurogenic Commitment
Transcriptome analysis of somatic stem cells and their progeny is fundamental to identify new factors controlling proliferation versus differentiation during tissue formation. Here we generated a combinatorial, fluorescent reporter mouse line to isolate proliferating neural stem cells, differentiati...
ORGANISM(S): Mus musculus 
2013-11-18 | E-GEOD-51606 | biostudies-arrayexpress
Genomicsena-DATASET-BLUEPRINT-13-09-2016-12:21:58:649-53 - samples
BLUEPRINT DNA methylation profiles of monocytes, T cells and B cells in type 1 diabetes-discordant monozygotic twins (Bisulfite-Seq data).
EGAD00001002682 | EGA
TranscriptomicsDeciphering the molecular immune response to COVID-19 using single cell multi-omics
Multi-omics single-cell profiling of surface proteins, gene expression and lymphocyte immune receptors from hospitalised COVID-19 patient peripheral blood immune cells and healthy controls donors. Identification of the coordinated immune cell compositional and state changes in response to SARS-CoV-2...
ORGANISM(S): Homo sapiens 
2021-03-17 | E-MTAB-10026 | biostudies-arrayexpress
GenomicsWP8_DNA_Methylation_450K_UCL
BLUEPRINT DNA methylation profiles of monocytes, T cells and B cells in type 1 diabetes-discordant monozygotic twins
EGAD00010001025 | EGA
GenomicsBLUEPRINT DNA methylation profiles of monocytes, T cells and B cells in type 1 diabetes-discordant monozygotic twins
BLUEPRINT DNA methylation profiles of monocytes, T cells and B cells in type 1 diabetes-discordant monozygotic twins
EGAS00001001598 | EGA
UnknownLoss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2
Not available
S-SCDT-EMBOR-2020-51913-T | biostudies-other
UnknownPerformance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia.
Not available
S-EPMC9877422 | biostudies-literature
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