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TranscriptomicsTranscription profiling of human CD14+ CD16- and CD14low CD16+ monocytes from patients with Sjogrens syndrome and normal controls
Sjogren's syndrome is an autoimmune disease, characterized by complaints such as xerostomia and keratoconjunctivitis sicca. In other autoimmune diseases such as diabetes and SLE, monocyte abberancies have been described. Therefore, this study aimed at studying the monocyte compartment in Sjogren's S...
ORGANISM(S): Homo sapiens 
2008-08-04 | E-MEXP-1242 | biostudies-arrayexpress
TranscriptomicsPrimary Sjogren's syndrome study
The objective of the study was to identify gene expression signatures in minor salivary glands (MSGs) from patients with primary Sjogren's syndrome (SS). METHODS: A 16K complementary DNA microarray was used to generate gene expression profiles in MSGs obtained from 10 patients with primary SS and 10...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2073 | biostudies-arrayexpress
TranscriptomicsViral Profiles in Sjogren's Syndrome
A study was designed to further define the viral landscape within Sjogren's Syndrome (pSS) affected salivary gland tissue to identify potential viral-mediated triggers in the pathogenesis of this autoimmune disease. Viral Probes for Vertebrate Infecting Viral Families
ORGANISM(S): Viruses 
2017-05-01 | E-GEOD-77599 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing from human salivary glands from Sjogren's disease patients recruited in the TRACTISS randomized clinical trial
Sjogren's disease patients received Rituximab (anti-CD20 depleting monoclonal antibody) or placebo treatment. This study aims to identify the transcriptomic features of salivary gland biopsies, the target tissue of the autoimmune response in Sjögren’s disease. It examines transcriptomic changes in s...
ORGANISM(S): Homo sapiens 
2025-06-30 | E-MTAB-15225 | biostudies-arrayexpress
ProteomicsProteomics analysis of tears and saliva from Sjogren’s syndrome patients
Sjogren’s syndrome (SS) is characterized by dysfunctional mucous membranes and dysregulated moisture-secreting glands resulting in various symptoms, including dry mouth and dry eyes. Here, we wanted to profile and compare the tears and saliva proteomes of SS patients to healthy controls. Tear and sa...
ORGANISM(S): Homo sapiens (Human) 
2021-10-04 | PXD028922 | Pride
Proteoglycan 4 Lubricin Proteomics Sjogren’s syndrome Protease Protease inhibitor Prg4 Saliva Tears 
GenomicsAutoantibodies in sera from Sjogren's syndrome mice
Autoantibodies in sera from Sjogren's syndrome mice
PRJNA685989 | ENA
GenomicsDiscovery and Characterization of Genetic Risk Loci in Sjogren's syndrome
Discovery and Characterization of Genetic Risk Loci in Sjogren's syndrome
PRJNA786687 | ENA
GenomicsDiscovery and Characterization of Genetic Risk Loci in Sjogren's syndrome
Discovery and Characterization of Genetic Risk Loci in Sjogren's syndrome
PRJNA786688 | ENA
GenomicsIgG Autoantigen Array using sera from primary Sjogren's syndrome patients and non-Sjogren's syndrome controls
IgG Autoantigen Array using sera from primary Sjogren's syndrome patients and non-Sjogren's syndrome controls
PRJNA989578 | ENA
ProteomicsHuman salivary extracellular vesicles LC-MS/MS
This study aims at the quantitative analysis of human salivary extracellular vesicle (EV) content from patients affected by primary Sjogren's syndrome (pSS) in order to determine candidate biomarkers for disease diagnosis, patient stratification and monitoring.
ORGANISM(S): Homo sapiens (Human) 
2021-06-10 | PXD025649 | Pride
Human Saliva Extracellular vesicles Sjogren's syndrome Swath-ms 
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