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ProteomicsProteomic analysis of serum small extracellular vesicles of individual mice for longitudinal investigations
Characterization of small extracellular vesicles (sEV) from individual mice for the longitudinal investigation of proteome changes in a mouse model of Glioblastoma Multiforme (GBM). We first compared precipitation and size exclusion chromatography (SEC) for sEV purification from 100ul of mouse serum...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-30 | PXD016473 | Pride
Glioblastoma Proteomics Size exclusion chromatography Small extracellular vesicles Serum Mouse Biomarker discovery 
ProteomicsLabel-free proteome analysis of small extracellular vesicles (sEV) expressing different HRS mutants.
Label-free proteome analysis of small extracellular vesicles (sEV) derived from WM9 cells expressing different HRS mutants: wild type (HRSWT), phospho-deficient (HRSS345A), and phospho-mimetic mutant HRS (HRSS345D).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-16 | MSV000088846 | MassIVE
ProteomicsDistinct proteomic profiles of T cell-derived small extracellular vesicles from plasma of melanoma patients and healthy donors
Small extracellular vesicles (sEV) released by T cells play a key role in immune regulation. In-depth characterization of T cell-derived sEV in human plasma requires their isolation from a heterogeneous mixture of circulating vesicles by immune capture with anti-CD3 antibody. Here, we compared prote...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD052476 | Pride
Immunocapture  cd3+ antigen  plasma exosomes  high-resolution mass spectrometry  melanoma  small extracellular vesicles (sev)  t-cell derived exosomes 
TranscriptomicsMiRNA signatures associated with lung involvement in systemic sclerosis (Small RNA-Seq)
There is a pressing need to identify early biomarkers of lung involvement in systemic sclerosis (SSc) to start as soon as possible antifibrotic therapy. We aimed to identify extracellular vesicle-derived microRNAs (EV-miRNAs) that are differentially expressed between SSc patients with and without in...
ORGANISM(S): Homo sapiens 
2024-09-15 | E-MTAB-14290 | biostudies-arrayexpress
ProteomicsSmall Extracellular Vesicles Derived from Human Trabecular Meshwork Stem Cells are distinct from TM Cells in their Proteome Cargo and Function
Glaucoma is an optic neuropathy, the second leading cause of irreversible blindness worldwide. In our earlier studies, we demonstrated the isolation and functional efficacy (wound healing and anti-oxidant potential) of small extracellular vesicles (sEV) from the adult tissue-resident stem cells of t...
ORGANISM(S): Homo sapiens (Human) 
2025-06-13 | PXD059934 | Pride
Proteomics Glaucoma Small extracellular vesicles Trabecular meshwork stem cells 
ProteomicsComparative proteomic analysis identifies specific signature proteins in small extracellular vesicles from granulocytes and CD4+ T cell subpopulations
Proteomic analysis of small extracellular vesicles (sEV) is a powerful tool for the characterization of cell-to-cell signalling. While several studies describe the proteome profile of different immune cell types, none have analysed the content of their delivered sEV. The aim of the present study was...
ORGANISM(S): Homo sapiens (Human) 
2025-02-18 | PXD046108 | Pride
Th17 Exosomes Th2 Th1 Proteomics Eosinophils Sev Neutrophils 
ProteomicsLC-MS of small extracellular vesicles (sEVs) secreted by mock- vs. Zika virus (ZIKV)-infected JEG-3 cells
Proteomics profiling of small extracellular vesicles secreted by mock- vs. ZIKV (PRVABC59)-infected JEG-3 cells.
ORGANISM(S): Homo sapiens (Human) 
2023-09-12 | PXD041807 | Pride
Small extracellular vesicles (sevs) Zika virus (zikv) Jeg-3 
ProteomicsIsolation and Comprehensive Analysis of Cochlear Tissue-derived Small Extracellular Vesicles
Label-free quantitative proteomics analysis of CDsEVs, with the same amount of protein of cochlear tissues used as the control
ORGANISM(S): Mus Musculus 
2024-10-04 | PXD056591 |
TranscriptomicsmiR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto’s thyroiditis
Hashimoto’s thyroiditis (HT) is an organ-specific autoimmune disease characterized by lymphocyte infiltration that destroys thyrocyte cells. To date, the underlying mechanisms responsible for these processes are incompletely understood. Here, we identified that miR-142-3p encapsulated in T lymphocyt...
ORGANISM(S): Homo sapiens 
2026-01-18 | E-MTAB-12659 | biostudies-arrayexpress
ProteomicsSmall extracellular vesicles from A549 cells
For a study comparing small extracellular vesicles (sEVs) from WI-38 and A549 cells. The proteome of A549 sEVs were obtained to find proteins that could distinguish WI-38-derived sEVs from A549-derived sEVs. These protein markers were used as proof-of-principle biomarkers for a FRET-based sEV biomar...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-20 | MSV000089509 | MassIVE
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