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Proteomic data from mouse lung; Treated with wild-type and mutant H7N9 and mockulum; Time points 1, 2, 4 & 7 days; 5 biological replicates
ORGANISM(S): Homo sapiens (Human) 
2017-05-24 | PXD006265 | Pride
Influenza infection is a worldwide health and financial burden posing a significant risk to the immune-compromised, obese, diabetic, elderly, and pediatric populations. We identified increases in glucose metabolism in the lungs of pediatric patients infected with respiratory pathogens. Using quantit...
ORGANISM(S): Homo sapiens (Human) 
2017-05-24 | PXD006263 | Pride
In response to influenza infection we found that dendritic cells (DCs), cells that are critical in mounting an effective immune response, undergo a profound metabolic shift. DCs alter the concentration and location of hundreds of proteins, including c-MYC, mediating a shift to a highly glycolytic ph...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD013690 | Pride
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