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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
ProteomicsMining waste streams of food production for bioactive plant polysaccharides that affect the fitness and expressed activities of targeted human gut microbes
Mining waste streams of food production for bioactive plant polysaccharides that affect the fitness and expressed activities of targeted human gut microbes
ORGANISM(S): Microbiota (ncbitaxon:13613) Mus Musculus (ncbitaxon:10090) 
2018-04-18 | MSV000082287 | MassIVE
TranscriptomicsTranscriptional Alterations of Hamstring Muscle Contractures in Children with Cerebral Palsy
Cerebral palsy is primarily an upper motor neuron disease that results in a spectrum of progressive movement disorders. Secondary to the neurological lesion, muscles from patients with cerebral palsy are often spastic and form debilitating contractures that limit range of motion and joint function....
ORGANISM(S): Homo sapiens 
2012-11-21 | E-GEOD-31243 | biostudies-arrayexpress
ProteomicsThe proteome of normal human sclera
The optic nerve is a white matter tract that conveys visual information to the brain. The sclera comprises the white, protective outer layer of the eye. A characterization of the proteome of normal human retrobulbar optic nerve and sclera may facilitate studies of the eye. We conducted a proteomic a...
ORGANISM(S): Homo sapiens (Human) 
2020-11-24 | PXD022661 | Pride
Human Sclera Proteome 
ProteomicsThe proteome of normal human sclera
The sclera provides an opaque protective coat for five-sixths of the surface of the human eye. A detailed investigation of the proteome of the normal human sclera may provide insights into the biology and pathophysiology of the sclera. We conducted an in-depth proteomic analysis of sclera from five ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD004223 | Pride
Collagen Proteome Myopia Sclera Eye / human 
UnknownAmerican Society of Clinical Oncology Statement: A Conceptual Framework to Assess the Value of Cancer Treatment Options.
Not available
S-EPMC5015427 | biostudies-literature
ProteomicsHigh-throughput and high-efficiency sample preparation for single-cell proteomics using a nested nanowell chip
Development and evaluation of nested nanowell (N2) chip in single-cell proteomics. The newly designed chip helps to improve the sensitivity and robustness of the tandem mass tag labeling approach by sizing down wells.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-02-04 | MSV000086809 | MassIVE
ProteomicsHigh-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform
Single cell proteomics data from three murine cell lines (Raw, SVEC4-10, C10) and HeLa cell lysate. Samples were digested with trypsin and labeled with TMT 10-Plex on a small scale using nanoPOTS, followed by LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-07-19 | MSV000084110 | MassIVE
ProteomicsOuter membrane vesicles catabolize lignin-derived aromatic compounds in Pseudomonas putida KT2440
Lignin modifications and the exoproteome of three aromatic catabolic bacteria: Pseudomonas putida KT2440, Rhodoccocus jostii RHA1, and Amycolatopsis sp. ATCC 39116. Samples were digested with trypsin, then analyzed by LC-MS/MS. Data was searched with MSGF+ and abundances inferred using PNNL's DMS an...
ORGANISM(S): Pseudomonas Putida Kt2440 (ncbitaxon:160488) Amycolatopsis Sp. Atcc 39116 (ncbitaxon:385957) Rhodococcus Jostii Rha1 (ncbitaxon:101510) 
2019-11-01 | MSV000084524 | MassIVE
ProteomicsFacile one-pot nanoproteomics for label-free proteome profiling of 50-1000 mammalian cells
We report a facile one-pot nanoproteomics method termed SOPs-MS (Surfactant-assisted One-Pot sample processing at the standard volume coupled with MS) for convenient proteome profiling of 50-1000 mammalian cells. Building upon our recent development of SOP-MS for label-free single-cell proteomics at...
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2022-05-11 | PXD025918 | JPOST Repository
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