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ProteomicsStage-specific protein regulation during somatic embryo development of Carica papaya L. ‘Golden’
Somatic embryogenesis is an important biotechnological technique for large-scale propagation of elite genotypes. Correlations of stage-specific compounds associated with somatic embryo development can help elucidate the ontogenesis of Carica papaya L. somatic embryos and improve tissue culture proto...
ORGANISM(S): Carica papaya 
2020-11-12 | PXD021107 | Pride
C. papaya Polyamines Somatic embryogenesis Label-free proteomics 
ProteomicsProteomic analysis of somatic embryo development in Musa spp. cv. Grand Naine (AAA)
Somatic embryos are very much similar to zygotic counterparts in many morphological aspects and the somatic embryos are derived from somatic cells by undergoing various metabolic regulations. The somatic embryos have been used in artificial seed technology, genetic engineering and germplasm conserva...
ORGANISM(S): Musa acuminata AAA Group 
2020-03-16 | PXD015551 | Pride
Proteomics Development Somatic embryos Banana 
ProteomicsFunctional analysis of somatic variants found in endometrial tumor-specific ER-alpha enhancers
Biological implications of healthy- and tumor-specific ERα cistromes in endometrial tumors have largely been understudied. Moreover, the functional impact of non-coding somatic variants has commonly been underexplored and remained elusive. This study is aimed to provide functional interpretation of ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-15 | PXD029822 | Pride
Enhancers Endometrial cancer Er-alpha Somatic variants 
TranscriptomicsTranscription profiling of Cyclamen persicum zygotic embryo, callus and somatic embryo
The goal of the experiment was to investigate impact of the apoplast on somatic embryogenesis in Cyclamen persicum
ORGANISM(S): Cyclamen persicum 
2010-04-20 | E-TABM-837 | biostudies-arrayexpress
TranscriptomicsIncomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES) cells, but recent reports indicate that there may be important differences between them. We carried out a systematic comparison of human iPS cells generated from hepatocytes (representative of endoderm), skin fi...
ORGANISM(S): Homo sapiens 
2011-04-17 | E-GEOD-23034 | biostudies-arrayexpress
ProteomicsSS18 regulates pluripotent-somatic transition through phase separation
The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the identification of SS18 as a regulator for pluripotent to somatic transition or PST by CRISPR-based whole genome screens. Mechanistically, SS18 forms m...
ORGANISM(S): Mus Musculus 
2021-05-23 | PXD026208 |
ProteomicsCharacterization and functional differentiation of colostrum, transition milk, and mature milk somatic cells proteomes in multiparous Murrah buffaloes
The objective of the present study was to examine the proteome dynamics of somatic cells from colostrum to mature milk. Milk somatic cells are a mixture of mammary epithelial cells (MECs) and immune cells, secreted in milk during milking. Besides protecting the mammary gland, the milk somatic cells ...
ORGANISM(S): Bos taurus (Bovine) 
2025-07-14 | PXD054309 | Pride
Milk somatic cells Proteomics Transitional milk Murrah buffaloes Colostrum Mature milk Lc-ms/ms 
TranscriptomicsUNG shapes the specificity of AID-induced somatic hypermutation
This SuperSeries is composed of the following subset Series: GSE39108: UNG shapes the specifity of AID-induced somatic hypermutation in non B cells GSE39114: UNG shapes the specifity of AID-induced somatic hypermutation in B cells Refer to individual Series
ORGANISM(S): Mus musculus 
2012-07-04 | E-GEOD-39115 | biostudies-arrayexpress
TranscriptomicsEndogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
Small interfering RNAs (siRNAs) direct RNA interference (RNAi) in eukaryotes. In flies, somatic cells produce siRNAs from exogenous double-stranded RNA as a defense against viral infection. Here, we identify 21-nt long, endogenous siRNAs (endo-siRNAs) corresponding to transposons and heterochromatic...
ORGANISM(S): Drosophila melanogaster 
2008-04-10 | E-GEOD-11019 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells (HSCs), progenitor cells (HPCs), and granulocytes somatic cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer
Since the creation of Dolly, the first sheep cloned via somatic cell nuclear transfer (SCNT), in 1997, more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1-5%) is that the clones are likely derived from adult stem...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5677 | biostudies-arrayexpress
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