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ProteomicsAccurate, Sensitive, and Precise Multiplexed Proteomics using the Complement Reporter Ion Cluster
Quantitative analysis of proteomes across multiple time points, organelles, and perturbations is essential for understanding both fundamental biology and disease states. The development of isobaric tags (e.g. TMT) have enabled the simultaneous measurement of peptide abundances across several differe...
ORGANISM(S): Homo sapiens (Human) 
2018-04-23 | PXD009342 | Pride
Ms3 Tmtc Ms2 Tmt Quantitative multiplexed proteomics Label free 
ProteomicsQuantitative Proteomics for Xenopus Embryos
Sample preparation, instrument analysis and maxquant data analysis of TMT MultiNotch MS3
ORGANISM(S): Xenopus laevis (African clawed frog) 
2018-09-03 | PXD007915 | Pride
Xenopus laevis tmt multinotch ms3 sample preparation data analysis maxquant 
ProteomicsTransitions in the proteome and phospho-proteome during Xenopus laevis development.
Vertebrate development from an egg to a complex multi-tissue million-cell organism is supported by multiple phases of genome-scale remodeling of the repertoire of proteins and their post-translational modifications, yet so far we know little about these phases. In this paper we present comprehensive...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2025-07-14 | PXD060481 | Pride
Tmt Development Eclipse Lumos Xenopus laevis 
ProteomicsSynergy Between TNFα and Proteostatic Stress Drives Cell Death and Guard Immunity
The production and sensing of type I interferons (IFN-I) are critical for antiviral defense, yet most virus-infected cells do not produce IFN-I or upregulate IFN-stimulated genes. Using quantitative proteomics and global protein synthesis measurements, we show that productive viral infection globall...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-05 | PXD053765 | Pride
Orbitrap eclipse Hsv Viromics Cflip 
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