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ProteomicsAccurate, Sensitive, and Precise Multiplexed Proteomics using the Complement Reporter Ion Cluster
Quantitative analysis of proteomes across multiple time points, organelles, and perturbations is essential for understanding both fundamental biology and disease states. The development of isobaric tags (e.g. TMT) have enabled the simultaneous measurement of peptide abundances across several differe...
ORGANISM(S): Homo sapiens (Human) 
2018-04-23 | PXD009342 | Pride
Ms3 Tmtc Ms2 Tmt Quantitative multiplexed proteomics Label free 
UnknownEffectiveness of a government-organized and hospital-initiated treatment for multidrug-resistant tuberculosis patients--a retrospective cohort study.
Not available
S-EPMC3581541 | biostudies-literature
UnknownAccurate, Sensitive, and Precise Multiplexed Proteomics Using the Complement Reporter Ion Cluster.
Not available
S-EPMC6220677 | biostudies-literature
UnknownDissecting Detergent-Insoluble Proteome in Alzheimer's Disease by TMTc-Corrected Quantitative Mass Spectrometry.
Not available
S-EPMC10392608 | biostudies-literature
UnknownImpact of universal drug susceptibility testing and effective management of multidrug-resistant tuberculosis in Taiwan.
Not available
S-EPMC6445419 | biostudies-literature
UnknownTreatment Outcomes of Multidrug-Resistant Tuberculosis in Taiwan: Tackling Loss to Follow-up.
Not available
S-EPMC6030934 | biostudies-literature
UnknownEvaluation of Protein Identification and Quantification by the diaPASEF Method on timsTOF SCP.
Not available
S-EPMC12379512 | biostudies-literature
ProteomicsEvidence for widespread cytoplasmic structuring into mesoscopic condensates
Eukaryotic cytoplasm organizes itself via membrane-bound organelles and membrane-less biomolecular condensates (BMCs). Known BMCs exhibit liquid-like properties and are typically visualized on the scale of ~1 µm. They have been studied mostly by microscopy, examining select individual proteins. Here...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2023-11-02 | PXD029879 | Pride
Orbitrap fusion lumos Filtration Liquid-liquid phase separation Xenopus laevis 
ProteomicsDifferential nuclear import sets the timing of protein access to the embryonic genome
During early embryonic cell divisions, the total nuclear volume doubles with each cycle. At a critical volume ratio between the nucleus and cytoplasm, embryos start transcribing their genome in a reproducible and sequential manner. However, the underlying molecular mechanism for these well-timed eve...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-08-30 | PXD028069 | Pride
Multiplexed quantitative proteomics Lc-ms Xenopus embryo Nucleocytoplasmic partitioning Zygotic gene activation Early embryogenesis Nuclear import 
ProteomicsDifferential nuclear import sets the timing of protein access to the embryonic genome
During early embryonic cell divisions, the total nuclear volume doubles with each cycle. At a critical volume ratio between the nucleus and cytoplasm, embryos start transcribing their genome in a reproducible and sequential manner. However, the underlying molecular mechanism for these well-timed eve...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-08-30 | PXD036403 | Pride
Multiplexed quantitative proteomics Lc-ms Xenopus embryo Nucleocytoplasmic partitioning Zygotic gene activation Early embryogenesis Nuclear import 
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