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ProteomicsComprehensive peptide analysis of mouse brain striatum identifies novel sORF-encoded polypeptides
Bio-active peptides are involved in the regulation of most if not all physiological processes in the body. Classical bio-active peptides (CBAPs) are mostly cleaved from a larger precursor protein and stored in secretion vesicles from which they are released in the extracellular space to exert there ...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-10 | PXD008526 | Pride
5’utr Neuropeptides Peptidomic approach Ribosome profiling Bio-active peptides Sorf Seps 
ProteomicsBlautia producta displays great plasticity of short open reading frame-encoded peptides under different environmental conditions
Short open reading frames (sORF) have the potential to encode small proteins in the human gut microbiome, but their role in this environment is rarely understood. These small proteins, known as sORF-encoded peptides (SEP), are less than or equal to 100 amino acids in length. Using bottom-up proteomi...
ORGANISM(S): Blautia producta ATCC 27340 = DSM 2950 
2023-09-19 | PXD041979 | Pride
Sep Top-down proteomics Sorf-encoded peptides Ibd Inflammation Bottom-up proteomics Proteoform Short open reading frames Bacterial proteomics 
Proteomicsanalysis combined with fragment intensity predictions results in improved identification of classical bioactive peptides and sORF-encoded peptides
Bioactive peptides exhibit key roles in a wide variety of complex processes, such as regulation of body weight, learning, aging and innate immune response. Next to the classical bioactive peptides, emerging from larger precursor proteins by specific proteolytic processing, a new class of bio-active ...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-11 | PXD026584 | Pride
Spectral intensity prediction Micropeptide Proteogenomics Neuropeptide Timstof Peptidomics Sorf-encoded peptide (sep) Non-coding 
TranscriptomicsK562 polyA RNA-Seq
RNA-Seq reads and TopHat (Trapnell et al. Bioinformatics 2009) alignments of K562 cell-line transcriptome. These were used to validate the expression of short peptides idenitified by Mass-Spectrometry in K562 cells. K562 polyA+ RNA (Batch 1) and total RNA (batch 2) was purchased from Ambion. We use...
ORGANISM(S): Homo sapiens 
2012-11-14 | E-GEOD-34740 | biostudies-arrayexpress
Genomics
RNA sequencing of Deinococcus radiodurans under radiation and oxidation
PRJNA833597 | ENA
UnknownMapping Start Codons of Small Open Reading Frames by N-Terminomics Approach.
Not available
S-EPMC11602987 | biostudies-literature
UnknownImproved Identification of Small Open Reading Frames Encoded Peptides by Top-Down Proteomic Approaches and De Novo Sequencing.
Not available
S-EPMC8197016 | biostudies-literature
GenomicsCellular function of the GndA small open reading frame-encoded polypeptide during heat shock
Cellular function of the GndA small open reading frame-encoded polypeptide during heat shock
PRJNA1124095 | ENA
ProteomicsMass spectrometry-based draft of the mouse proteome
Quantitative draft map of the proteomes of 41 healthy tissues of the animal model Mus musculus and a panel of 66 murine pancreatic ductal adenocarcinoma cell lines and. Our in-depth analysis provides evidence for proteins encoded by >16,000 genes (~76% of the total annotated protein-coding genes), w...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-01 | PXD030983 | Pride
Mouse Phosphoproteome Mus musculus Drug sensitivity Proteome Pdac Pancreatic cancer Radiation sensitivity 
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