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TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
UnknownARA-PEPs: a repository of putative sORF-encoded peptides in Arabidopsis thaliana.
Not available
S-EPMC5240266 | biostudies-literature
ProteomicsComprehensive peptide analysis of mouse brain striatum identifies novel sORF-encoded polypeptides
Bio-active peptides are involved in the regulation of most if not all physiological processes in the body. Classical bio-active peptides (CBAPs) are mostly cleaved from a larger precursor protein and stored in secretion vesicles from which they are released in the extracellular space to exert there ...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-10 | PXD008526 | Pride
5’utr Neuropeptides Peptidomic approach Ribosome profiling Bio-active peptides Sorf Seps 
Proteomicsanalysis combined with fragment intensity predictions results in improved identification of classical bioactive peptides and sORF-encoded peptides
Bioactive peptides exhibit key roles in a wide variety of complex processes, such as regulation of body weight, learning, aging and innate immune response. Next to the classical bioactive peptides, emerging from larger precursor proteins by specific proteolytic processing, a new class of bio-active ...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-11 | PXD026584 | Pride
Spectral intensity prediction Micropeptide Proteogenomics Neuropeptide Timstof Peptidomics Sorf-encoded peptide (sep) Non-coding 
UnknownThe sORF-Encoded Peptides, ATP Synthase Subunits, Facilitate WSSV Duplication in Shrimp.
Not available
S-EPMC9692589 | biostudies-literature
UnknownProteogenomic discovery of sORF-encoded peptides associated with bacterial virulence in Yersinia pestis.
Not available
S-EPMC8563848 | biostudies-literature
ProteomicsProteogenomic Discovery of sORF-encoded Peptides in Yersinia pestis Reveals Regulatory Phenotype on Bacterial Virulence
An integrated pipeline for discovery of SEPs were established including modules of prediction, discovery and curation.
ORGANISM(S): Yersinia Pestis Biovar Microtus Str. 91001 
2021-10-03 | PXD028891 |
GenomicsPhloem proteomics to identify small Open Reading Frame (sORF)-encoded peptides with a putative role in the control of flowering time in Arabidopsis
Phloem proteomics to identify small Open Reading Frame (sORF)-encoded peptides with a putative role in the control of flowering time in Arabidopsis
PRJNA1336239 | ENA
ProteomicsBRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III
The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly expanding the known proteome at the lower end of the size distribution. Here, we show that the mitochondrial proteome is enriched for proteins smaller than 100 a.a. (defined as SEPs). Using a prediction and validatio...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Mus musculus (Mouse) 
2020-03-18 | PXD016718 | Pride
Sorf Oxphos Uorf Mitochondria Zebrafish 
UnknownRPS27, a sORF-Encoded Polypeptide, Functions Antivirally by Activating the NF-κB Pathway and Interacting With Viral Envelope Proteins in Shrimp.
Not available
S-EPMC6928191 | biostudies-literature
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