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UnknownSafety Profile of a Cognitively Unimpaired Older Population with Elevated Cerebral Amyloid in a 4.5-Year Clinical Trial.
Not available
S-EPMC11266256 | biostudies-literature
ProteomicsSmall molecule-induced polymerization triggers degradation of BCL6
Most small-molecule protein degraders act as interface stabilizers ‘molecular glues’ between E3 ubiquitin ligases and target proteins to induce ternary complex formation and ubiquitin-dependent target protein degradation. Here we report polymerization as a novel mechanism for small molecule-induced ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-20 | PXD016185 | Pride
Polymerization Bcl6 Molecular glue Siah1 Ubiquitin Btb Dlbcl 
UnknownSmall-molecule-induced polymerization triggers degradation of BCL6.
Not available
S-EPMC7816212 | biostudies-literature
UnknownAmyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials.
Not available
S-EPMC4553028 | biostudies-literature
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
UnknownA computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI.
Not available
S-EPMC4461537 | biostudies-literature
UnknownUsing CSF biomarkers to replicate genetic associations in Alzheimer's disease.
Not available
S-EPMC3150628 | biostudies-literature
UnknownGrowth differences between North American and European children at risk for type 1 diabetes.
Not available
S-EPMC3335929 | biostudies-literature
UnknownHydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial.
Not available
S-EPMC4225544 | biostudies-literature
UnknownThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Not available
S-EPMC3145073 | biostudies-literature
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