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ProteomicsCST interacts with the cohesin complex and promotes chromosome cohesion
Sister chromatid cohesion (SCC), the pairing of sister chromatids following DNA replication until mitosis, is established by loading of the cohesin complex on newly replicated chromatids. Cohesin must then be maintained until mitosis to prevent segregation defects and aneuploidy. However, how SCC is...
ORGANISM(S): Homo sapiens (Human) 
2021-07-28 | PXD026264 | Pride
Fork stalling Chromosome cohesion Cst Ctc1 Stn1 Cohesin Ten1 Dna replication 
UnknownKetamine as the anaesthetic for electroconvulsive therapy: the KANECT randomised controlled trial.
Not available
S-EPMC5451642 | biostudies-literature
UnknownRecent Diagnosis, Lower Rates of HIV Disclosure, and High Technology Access in Pregnant Adolescent Girls and Young Women Living With HIV: A Descriptive Study.
Not available
S-EPMC7985848 | biostudies-literature
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
UnknownMolecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
Not available
S-EPMC6369924 | biostudies-literature
UnknownGenome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease.
Not available
S-EPMC4740183 | biostudies-literature
UnknownClinical and genetic association of serum ceruloplasmin with cardiovascular risk.
Not available
S-EPMC3262121 | biostudies-literature
UnknownComparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine.
Not available
S-EPMC4035110 | biostudies-literature
UnknownClinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk.
Not available
S-EPMC3499946 | biostudies-literature
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