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TranscriptomicsMurine Embryonic Fibroblasts: Wild-type Stmn1 versus null Stmn1 Cells
Background: Stathmin (STMN1) protein functions to regulate assembly of the microtubule cytoskeleton by destabilizing microtubule polymers. Stathmin over-expression has been correlated with cancer stage progression, while stathmin depletion leads to death of some cancer cell lines in culture. In cont...
ORGANISM(S): Mus musculus 
2009-07-31 | E-GEOD-17432 | biostudies-arrayexpress
TranscriptomicsMurine Embryonic Fibroblasts: Wild-type Stmn1 versus null Stmn1 Cells
Background: Stathmin (STMN1) protein functions to regulate assembly of the microtubule cytoskeleton by destabilizing microtubule polymers. Stathmin over-expression has been correlated with cancer stage progression, while stathmin depletion leads to death of some cancer cell lines in culture. In cont...
ORGANISM(S): Mus musculus 
2009-07-31 | GSE17432 | GEO
GenomicsNovel therapeutic strategy targeting STMN1 using chlorambucil-conjugated pyrrole-imidazole polyamide in small cell lung cancer
Novel therapeutic strategy targeting STMN1 using chlorambucil-conjugated pyrrole-imidazole polyamide in small cell lung cancer
PRJNA1185706 | ENA
TranscriptomicsEffect of STMN1 knockdown on prostate cancer cell lines
STMN1 is is a highly conserved 18 KDa cytosolic phosphoprotein, involved in the control of cell proliferation, differentiation, motility, clonogenicity and survival. Over-expression of STMN1 has been shown to be a marker of poor outcome in nasopharyngeal, ovarian, estrogen receptor positive tamoxife...
ORGANISM(S): Homo sapiens 
2018-06-30 | GSE96523 | GEO
TranscriptomicsNovel therapeutic strategy targeting STMN1 using chlorambucil-conjugated pyrrole-imidazole polyamide in small cell lung cancer
Introduction Small-cell lung cancer (SCLC) is an aggressive malignancy and its treatment has not progressed over the decades. Stathmin 1 (TMN1) is a cytoplasmic phosphorylated protein that is specific to cancerous tissues and is associated with malignancy. Pyrrole-imidazole polyamide (PIP) compounds...
ORGANISM(S): Homo sapiens 
2025-08-18 | GSE281782 | GEO
TranscriptomicsSingle cell RNA-seq of Stmn1+ isthmal cells and Pgc+ chief cells to compare and characterize distinct gastric corpus stem cells at molecular level
The purpose of this single cell experiment is to compare and characterize at molecular level actively cycling stem cells in the isthmus and quiescent stem cells in the base of the mouse stomach corpus. The lineage tracing data from Stmn1-CreERT2 shows that Stmn1+ cells in the corpus isthmus include ...
ORGANISM(S): Mus musculus 
2019-08-14 | E-MTAB-6879 | biostudies-arrayexpress
ProteomicsChromokinesin KIF4A teams up with STMN1 to regulate abscission in a SUMO-dependent manner
Cell division ends when two daughter cells physically separate via abscission, the cleavage of the intercellular bridge. It is currently less clear how the anti-parallel microtubule bundles bridging daughter cells are severed. Here, we provide evidence for a novel abscission mechanism. We found that...
ORGANISM(S): Homo sapiens (Human) 
2020-07-14 | PXD007055 | Pride
Cytokinesis Abscission Kif4a Mitosis Human Stmn1 Sumo Lc-ms/ms 
UnknownImpact of Social Defeat Stress on DNA Methylation in Drd2, Nr3c1, and Stmn1 in Wild-type and Stmn1 Knock-out Mice.
Not available
S-EPMC8813314 | biostudies-literature
UnknownCENPA-driven STMN1 Transcription Inhibits Ferroptosis in Hepatocellular Carcinoma.
Not available
S-EPMC10412702 | biostudies-literature
UnknownSTMN1 Promotes Progesterone Production Via StAR Up-regulation in Mouse Granulosa Cells.
Not available
S-EPMC4897624 | biostudies-literature
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