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TranscriptomicsGene expression changes associated with progression and response in chronic myeloid leukemia
Chronic myeloid leukemia (CML) is a hematopoetic stem cell disease with distinct biological and clinical features. The biological foundation of the stereotypical progression from chronic phase through accelerated phase to blast crisis is poorly understood. We used DNA microarrays to compare gene exp...
ORGANISM(S): Homo sapiens 
2010-06-11 | E-GEOD-4170 | biostudies-arrayexpress
TranscriptomicsHP1 wa191.D.mel 3rd Instar Larvae Nuclei piwi2 mutant
modENCODE_submission_5061 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of the major histone modifications across the Drosophila melanogaster genome. The modificat...
ORGANISM(S): Drosophila melanogaster 
2013-03-06 | E-GEOD-44884 | biostudies-arrayexpress
ProteomicsMacrostomum bioadhesion - A mechanism for temporary bioadhesion
The flatworm Macrostomum lignano features a duo-gland adhesive system that allows it to repeatedly attach to and release from substrates in seawater within a minute. However, little is known about the molecules involved in this temporary adhesion. In this study, we showed that the attachment of M. l...
ORGANISM(S): Macrostomum lignano 
2019-02-15 | PXD012626 | Pride
Bioadhesives Flatworms Bioadhesion Platyhelminthes Detattchment 
TranscriptomicsSCL006,icSARS CoV Urbani or icSARS Bat SRBD (spike receptor binding domain from the wild type strain Urbani to allow for infection of human and non-human primate cells) infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV or the icSARS deltaORF6 mutant. Calu-3 cells were infected with either icSARS CoV or the cSARS Bat SRBD strain at MOI of 1.0. Cells samples were collected at 0, 7, 1...
ORGANISM(S): Homo sapiens 
2012-05-06 | E-GEOD-37827 | biostudies-arrayexpress
TranscriptomicsDevelopment pathway for skin resident memory CD103+CD8+ T cells
Tissue resident memory T cells (TRM) provide superior protection against infection localised to extra-lymphoid compartments in the body. Here we show that CD103+CD8+ TRM cells develop in skin from killer cell lectin-like receptor (KLR)G1-negative precursors that selectively infiltrate the epithelia...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-47045 | biostudies-arrayexpress
ProteomicsHuman non-small cell lung cancer cell line NCI-H661 DPPA2-4 rapid immunoprecipitation mass spectrometry (RIME, LC-MSMS)
To investigate DPPA2/4 bound proteins on chromatin we performed rapid immunoprecipitation mass spectrometry (RIME) following double crosslinking of chromatin in NCI-H661 non-small cell lung cancer cells clonal cell lines (Wild Type clones c51 & c52, DPPA2 knockout clones c41 & c42, DPPA4 knockout cl...
ORGANISM(S): Homo sapiens (Human) 
2026-03-31 | PXD070627 | Pride
Rime Dppa4 Non small cell lung cancer Ncih661 Dppa2 Human 
ProteomicsMALDI rat liver anticancer drug spiked-in dataset (imzML)
For the MALDI-MSI experiment, we selected 12 different drugs. The drugs were purchased from the LC Laboratories (Woburn, MA; CAS numbers: dabrafenib: 1195765-45-7, dasatinib: 302962-49-8, erlotinib: 183321-74-6, gefitinib: 184475-35-2, imatinib: 152459-95-5, lapatinib: 388082-78-8, pazopanib: 444731...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-06 | PXD016146 | Pride
Imzml ground truth spiked-in drugs 
UnknownIdentifying Where REDD+ Financially Out-Competes Oil Palm in Floodplain Landscapes Using a Fine-Scale Approach.
Not available
S-EPMC4898686 | biostudies-literature
TranscriptomicsTranscription profiling of pancreas from rats of four strains after drinking ethanol at various concentrations for twelve months
Male rats from one of four strains (Wistar, AA, HAD or P) were housed individually in standard hanging rodent cages (Ehret, Emmendingen, Germany) on a 12-hour light-dark cycle with lights on at 07:00 a.m.. Animals were provided with food (Sniff, Soest, Germany), tap water, 5, 10 and 20% (v/v) ethano...
ORGANISM(S): Rattus norvegicus 
2009-12-31 | E-MEXP-776 | biostudies-arrayexpress
TranscriptomicsImmortalized Human Hepatocyte (IHH) transcriptome response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08)
The purpose of this experiment was to obtain samples for transcriptome analysis using wild-type viruses: Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08). Overview of Experiment: Cells: Immortalized Human Hepatocytes (IHH); seed 60,000 cells per well in a 24-well plate. Infected with a multiplic...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-65573 | biostudies-arrayexpress
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