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ProteomicsCharacterization of a nonhuman primate model for the study of testicular peritubular cells – comparison with human testicular cells
Smooth-muscle-like peritubular cells make up the wall of semniferous tubules of men. These human testicular peritubular cells (HTPC) have been shown to fulfill different roles. They transport sperm, secrete various factors like GDNF (glial cell line derived neurotrophic factor) and are immunological...
ORGANISM(S): Callithrix jacchus 
2018-06-06 | PXD009394 | Pride
Testis Mktpc Marmoset monkey Peritubular testicular cells Maxquant Htpc Dda Proteome 
ProteomicsProteome analysis of satellite cells from DMD and WT pigs
Recent studies on the contribution of satellite cells (SC) to Duchenne muscular dystrophy (DMD) documented altered division capacities and impaired regeneration potential of SC in muscle tissue of DMD patients and animal models. Hence, it is crucial to unravel if SC-intrinsic effects trigger these d...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-06-30 | PXD059983 | Pride
Dystrophin Satellite cells Duchenne muscular dystrophy 
ProteomicsOxidative stress initiates hemodynamic change in CKD induced heart disease
Cardiovascular disease is highly prevalent in patients with chronic kidney disease (CKD) and responsible for approximately half of CKD-related deaths. The mechanisms underlying the detrimental impact of CKD on the heart are still incompletely understood, but CKD is associated with endocrinal, inflam...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-01-17 | PXD050994 | Pride
Chronic kidney disease Heart disease Heart 
ProteomicsImpact of Diabetes and CKD Comorbidity on Cardiac Mitochondrial function, Oxidative Stress, and Structural Remodeling
Both diabetes and chronic kidney disease (CKD) predispose individuals to cardiac remodeling and coronary microvascular dysfunction. Our previous studies in swine models have revealed significant alterations in microvascular and myocardial structure and function, along with increased oxidative stress...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-01-23 | PXD065331 | Pride
Chronic kidney disease Heart Diabetes Cardiac muscle 
ProteomicsProteome analysis of skeletal muscle of DMD, BMD and WT pigs
Duchenne muscular dystrophy is a fatal X-linked disease caused by mutations in the DMD gene, leading to the absence of dystrophin and progressive degeneration of skeletal and cardiac muscles. Pigs lacking DMD exon 52 (DMDΔ52) are a clinically severe model for DMD, mimicking molecular, functional, an...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-03-12 | PXD064879 | Pride
Duchenne muscular dystrophy Pig model Becker muscular dystrophy Muscle 
ProteomicsHuman Granulosa Cells Proteome
Human granulosa cells are follicular cells surrounding the oocyte. Human granulosa cells are retrieved during in vitro fertilization a process where patients undergo hormonal stimulation including FSH and LH/hCG stimulation. Under the influence of the luteinizing hormone (LH) a process called lutein...
ORGANISM(S): Homo sapiens (Human) 
2019-03-07 | PXD010658 | Pride
Human granulosa cells Bottom-up Corpus luteum Luteal cells Maxquant Shotgun proteomics Human reproduction Lc-ms/ms 
UnknownDemographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry.
Not available
S-EPMC3329234 | biostudies-literature
UnknownGlobal, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.
Not available
S-EPMC4561509 | biostudies-literature
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