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ProteomicsProteomic Time-Course Investigation into the Effects of Exposure of Mycobacterium smegmatis to Sub-Lethal Dose of Rifampicin
Drug susceptible Mycobacterium smegmatis (Mc2-155) was exposed to a sub-MIC concentration of antimycobacterial drug Rifampicin (treated) or DMSO (control). Cells were harvested at 30, 255 and 300 minutes post-exposure and the proteome at each time analysed using LC-MS/MS on a Thermo Q-Exactive.
ORGANISM(S): Mycobacterium Smegmatis Str. Mc2 155 (ncbitaxon:246196) 
2019-03-18 | MSV000083589 | MassIVE
TranscriptomicsInflammatory gene expression in response to sub-lethal ricin exposure in Balb/c mice
The toxin ricin has been shown to cause inflammatory lung damage, leading to pulmonary oedema and, at higher doses, mortality. In order to understand the genetic basis of this inflammatory cascade a custom microarray platform (1509 genes) directed towards immune and inflammatory markers was used to ...
ORGANISM(S): Mus musculus 
2009-08-19 | E-GEOD-17431 | biostudies-arrayexpress
GenomicsSub-Lethal levels of Gentamicin impacts gonococcal gene expression
Sub-Lethal levels of Gentamicin impacts gonococcal gene expression
PRJNA1234610 | ENA
ProteomicsProteomic Time-Course Investigation into the Effects of Exposure of Mycobacterium smegmatis to Sub-Lethal Dose of Rifampicin
Drug susceptible Mycobacterium smegmatis (Mc2-155) was exposed to a sub-MIC concentration of antimycobacterial drug Rifampicin (treated) or DMSO (control). Cells were harvested at 30, 255 and 300 minutes post-exposure and the proteome at each time analysed using LC-MS/MS on a Thermo Q-Exactive.
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2017-03-15 | PXD004197 | Pride
Mycobacterium smegmatis tuberculosis drug resistance sub-lethal sub-mic 
ProteomicsCell wall enrichment unveils proteomic changes in the cell wall during treatment of Mycobacterium smegmatis with sub-lethal concentrations of Rifampicin
In this study, we successfully developed two gel-free approaches to specifically look at cell wall proteins in Mycobacterium smegmatis. The cell wall was subjected to differential centrifugation, differential detergent solubilisation and phase separation to yield the genuine cell wall proteome. The ...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2019-04-09 | PXD008075 | Pride
Cell wall proteomics Mycobacteria Mass spectrometry Rifampicin Tb drugs Tb Sub lethal 
GenomicsTranscriptomic analysis of Salmonella Typhimurium exposed to sub-lethal sonophotocatalytic disinfection
Transcriptomic analysis of Salmonella Typhimurium exposed to sub-lethal sonophotocatalytic disinfection
PRJNA750728 | ENA
GenomicsTranscriptomic analysis of Acinetobacter baumannii exposed to sub-lethal Sono-Fenton inactivation
Transcriptomic analysis of Acinetobacter baumannii exposed to sub-lethal Sono-Fenton inactivation
PRJNA836858 | ENA
TranscriptomicsToxicogenomic effects of sub-lethal exposures of organophosphates on mouse liver cells [mRNA Expression]
In order to examine the long term effects of the OPs, murine liver cells (BNL CL.2, ATCC® TIB-73) have been exposed to sub-lethal doses of three OPs: diisopropylfluorophosphate (DFP) representative of sarin and soman, O,S-diethyl methylphosphonothioate (OSD) serving as a simulant for VX, and paraox...
ORGANISM(S): Mus musculus 
2016-02-24 | E-GEOD-78222 | biostudies-arrayexpress
TranscriptomicsToxicogenomic effects of sub-lethal exposures of organophosphates on mouse liver cells [miRNA Expression]
In order to examine the long term effects of the OPs, murine liver cells (BNL CL.2, ATCC® TIB-73) have been exposed to sub-lethal doses of three OPs: diisopropylfluorophosphate (DFP) representative of sarin and soman, O,S-diethyl methylphosphonothioate (OSD) serving as a simulant for VX, and paraox...
ORGANISM(S): Mus musculus 
2016-02-24 | E-GEOD-78223 | biostudies-arrayexpress
GenomicsLong noncoding RNA expression profiles in sub-lethal heat treated hepatoma carcinoma cells. (SMMC-7721 cells: sub-lethal heat treated vs. untreated)
Transcriptional profiling of SMMC-7721 cells comparing control untreated with sub-lethal heat treated cells (50°C for 10 min). Differentially expressed lncRNA and mRNA were measured with an Agilent Human lncRNA+mRNA Array V4.0 (4 × 180 K format) containing 41,000 lncRNAs and 34,000 mRNAs. Goal was t...
ORGANISM(S): Homo sapiens 
2017-05-27 | GSE99351 | GEO
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