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ProteomicsMulti-Omics Characterization of Colon Mucosa and Submucosa/Wall from Crohn’s Disease Patients
Crohn’s disease (CD) is a subtype of inflammatory bowel disease (IBD) characterized by transmural disease. The concept of transmural healing (TH) has been proposed as an indicator of deep clinical remission of CD and as a predictor of favorable treatment endpoints. Understanding the pathophysiology ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD050335 | Pride
Crohn’s disease  transmural healing  colon  mucosa  submucosa  wall  transcriptomics  proteomics  histology  isoform 
ProteomicsProteomic Analysis of Porcine Small Intestinal Submucosa Before and After Decellularization
Proteomic Analysis of Porcine Small Intestinal Submucosa Before and After Decellularization
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-06-14 | PXD079406 | Pride
Porcine Decellularization Small intestinal submucosa 
ProteomicsEffects of lipid diets on the metaproteome of the mice colon submucosa
Eight mice colon (submucosa) samples were submitted for iTRAQ labeling, high pH reversed phase fractionation and LC-MS/MS analysis.
ORGANISM(S): Mus musculus (Mouse) Bacteroidetes Firmicutes MN01-01 
2019-02-20 | PXD008165 | Pride
Lipid diet Metaproteome Submucosa Mice Colon Itraq 
TranscriptomicsTranscription profiling of pig endometrium from pregnant and non-pregnant sows
In an attempt to unveil part of the molecular processes controlling porcine placentation we have investigated the pregnancy induced gene expression in the porcine endometrium at Day 14 after insemination using the Affymetrix GeneChip® Porcine Genome Array. Experiment Overall Design: At Day 14 after ...
ORGANISM(S): Sus scrofa 
2009-10-23 | E-GEOD-18641 | biostudies-arrayexpress
GenomicsMulti-Omics Characterization of Colon Mucosa and Submucosa/Wall from Crohn's Disease Patients
Multi-Omics Characterization of Colon Mucosa and Submucosa/Wall from Crohn's Disease Patients
PRJNA1085261 | ENA
TranscriptomicsGenotyping of human chromosomal instability patterns discriminates rectal adenomas from carcinomas
Total mesorectal excision (TME) is the standard treatment for rectal cancer, while transanal endoscopic microsurgery (TEM) is a recently introduced surgical approach for the treatment of rectal adenomas. Incorrect preoperative staging before TEM is a problem. To identify genetic changes that migh...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-7946 | biostudies-arrayexpress
ProteomicsSmall intestinal submucosa-derived extracellular matrix as heterotopic scaffold for cardiovascular applications
Structural cardiac lesions are often surgically repaired using prosthetic patches, which can be of biological or synthetic nature. In the current clinical scenario, amongst biological patches, are gaining very much interest those derived from decellularization of xenogeneic scaffold. These patches m...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-03-11 | PXD038206 | Pride
Cardiac repair Cardiac surgery Tergitol Extracellular matrix (ecm) Triton x 100 Small intestinal submucosa (sis) Decellularization 
UnknownColonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment.
Not available
S-EPMC12376669 | biostudies-literature
ProteomicsA Comparative Proteomic Study of Decellularized Extracellular Matrix Biomaterials Derived from Porcine Vocal Fold and Small Intestinal Submucosa Tissue Source
Decellularized extracellular matrix (dECM) is used to make regenerative biomaterials. As the ECM markups vary across organs, derived dECM products may possess different molecular and biological profiles as well. This study aims to compare the proteomic profiles of dECM biomaterials derived from sma...
ORGANISM(S): Sus scrofa (Pig) 
2023-02-01 | PXD033621 | Pride
Vocal fold Porcine Small intestine submucosa Decellularized Decm Core matrisome Lc-ms/ms Extracellular matrix 
TranscriptomicsMulti-Omics Characterization of Colon Mucosa and Submucosa/Wall from Crohn's Disease Patients
Crohn’s disease (CD) is a subtype of inflammatory bowel disease (IBD) characterized by transmural disease. The concept of transmural healing (TH) has been proposed as an indicator of deep clinical remission of CD and as a predictor of favorable treatment endpoints. Understanding the pathophysiology ...
ORGANISM(S): Homo sapiens 
2024-03-15 | GSE261086 | GEO
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