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GenomicsToward More Translational Tumor Models: Breast dECM-Based 3D Systems Capture Native Microenvironmental Cues
Toward More Translational Tumor Models: Breast dECM-Based 3D Systems Capture Native Microenvironmental Cues
PRJNA1454498 | ENA
ProteomicsA Comparative Proteomic Study of Decellularized Extracellular Matrix Biomaterials Derived from Porcine Vocal Fold and Small Intestinal Submucosa Tissue Source
Decellularized extracellular matrix (dECM) is used to make regenerative biomaterials. As the ECM markups vary across organs, derived dECM products may possess different molecular and biological profiles as well. This study aims to compare the proteomic profiles of dECM biomaterials derived from sma...
ORGANISM(S): Sus scrofa (Pig) 
2023-02-01 | PXD033621 | Pride
Vocal fold Porcine Small intestine submucosa Decellularized Decm Core matrisome Lc-ms/ms Extracellular matrix 
TranscriptomicsToward More Translational Tumor Models: Breast dECM-Based 3D Systems Capture Native Microenvironmental Cues
Current 3D tumor models for aggressive breast cancers inadequately recapitulate the native tumor microenvironment (TME), leading to poor translational potential. There is a critical need for models capable of mimicking the unique biochemical signals present in the TME. To address this gap, breast ti...
ORGANISM(S): Homo sapiens 
2026-07-01 | GSE328288 | GEO
UnknownBone-Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation.
Not available
S-EPMC12790313 | biostudies-literature
UnknownLiver dECM-Gelatin Composite Bioink for Precise 3D Printing of Highly Functional Liver Tissues.
Not available
S-EPMC10455418 | biostudies-literature
ProteomicsComparative proteomic analysis of the composition of decellularized extracellular matrix (dECM) and dECM-based inks as compared to the native tissue
Regenerative medicine and tissue engineering approaches based on the use of 3D-bioprinted decellularized extracellular matrix (dECM) present the advantage of a relatively biomolecule-rich matrix, which directs cell growth and differentiation in a tissue-specific manner. However, little is known abou...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-15 | PXD059171 | Pride
Ecm 3d bioprinting Ink composition Decellularization Lc–ms/ms 
UnknownDevelopment of Photocurable NorHA-dECM Hybrid Hydrogels to Study Cell-Matrix Interactions.
Not available
S-EPMC12418418 | biostudies-literature
UnknownFabrication and Evaluation of Porous dECM/PCL Scaffolds for Bone Tissue Engineering.
Not available
S-EPMC10381742 | biostudies-literature
UnknownModulating Cell-Scaffold Interaction via dECM-Decorated Melt Electrowriting PCL Scaffolds.
Not available
S-EPMC12694446 | biostudies-literature
ProteomicsChemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues
Investigating ECM-regulated new ECM production has been challenging due to the proteomic background from the pre-existing biomaterial ECM. To address this issue the newly synthesized ECM proteins (newsECM) of two different bioengineered tumor models were analyzed: tumor tissues, built upon decellula...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2025-08-30 | PXD061871 | Pride
Chemoselective chemistry Newly-synthesized extracellular matrix Biomaterial Proteomics 
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