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TranscriptomicsComparison between Estrogen receptor positive and Estrogen receptor negative breast cancer samples
Comparison between Estrogen receptor positive and Estrogen receptor negative breast cancer samples Keywords: breast cancer type comparison 152 unique breast cancer tissue sample are included in the analysis. The total mRNA has been labeled with Cy5 and then hybridized on a two color arrays against t...
ORGANISM(S): Homo sapiens 
2008-09-17 | E-GEOD-10510 | biostudies-arrayexpress
TranscriptomicsEstablishment and Comparative Characterization of Novel Non-Small Cell Lung Cancer Cell Lines and Their Corresponding Tumor Tissue
Cell lines play an important role for studying tumor biology and novel therapeutic agents. We demonstrated that cell lines represent a useful and reliable in vitro system for studying basic mechanisms in lung cancer. Moreover, we presented 3 novel, comprehensively characterized SCC cell lines. Estab...
ORGANISM(S): Homo sapiens 
2011-08-30 | E-GEOD-25251 | biostudies-arrayexpress
TranscriptomicsSCREENING STUDY TO IDENTIFY DIAGNOSTIC MARKERS FOR LUNG CANCER IN ENDOBRONCHIAL LINING FLUID
We investigated whether biomarker analysis in endobronchial epithelial lining fluid (ELF) collected by bronchoscopic microsampling may be useful for a definitive preoperative diagnosis. Therefore we compared ELF samples close to nodule and from the contralateral site from patients with malignant or ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-27489 | biostudies-arrayexpress
TranscriptomicsVALIDATION STUDY TO VERIFY DIAGNOSTIC MARKERS FOR LUNG CANCER IN ENDOBRONCHIAL LINING FLUID
We investigated whether biomarker analysis in endobronchial epithelial lining fluid (ELF) collected by bronchoscopic microsampling may be useful for a definitive preoperative diagnosis. Therefore we compared ELF samples close to nodule and from the contralateral site from patients with malignant or ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-27553 | biostudies-arrayexpress
ProteomicsDysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficient Pex2 knockout Zellweger mice
In the project “Dysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficient Pex2 knockout Zellweger mice” label-free mass spectrometry proteomics was used to study the proteome in different regions of the central nervous system of wild-type and peroxisome-deficient Pex2 knock...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-28 | PXD063585 | Pride
Peroxisomes Brain Pex2 knockout mouse Cerebral cortex Cholesterol Cerebellum Cns Myelination Brainstem Zellweger syndrome Spinal cord Lc-ms/ms 
TranscriptomicsRenal Cell Carcinoma Differential Expression
We investigated the changes in gene expression accompanying the development and progression of kidney cancer using 31,500 element complementary DNA arrays. We measured expression profiles for paired neoplastic and non-cancerous renal epithelium samples from 37 individuals. Using an experimental desi...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-3 | biostudies-arrayexpress
GenomicsGenome-wide DNA methylation events in TMPRSS2:ERG fusion negative prostate cancers implicate an EZH2 dependent mechanism with miRNA-26a hypermethylation.
Prostate cancer is the second most common cancer among men worldwide. Alterations in the DNA methylation pattern can be one of the leading causes for prostate cancer formation. This study is the first high throughput sequencing study investigating genome-wide DNA methylation patterns in a large coho...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEOD-35342 | biostudies-arrayexpress
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