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Ceramides are potent influencers of cell fate and function; however, their direct molecular target(s) and mechanism of action are poorly understood. In this study, we treated primary proximal tubule epithelial cells with C2-ceramide (50uM) or its precursor C2-dihydroceramide (50uM) and used proteome...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD067617 | Pride
The lymphatic vasculature is critical for lung function, but defects in lymphatic functionin the pathogenesis of lung disease is understudied. To further assess the contribution of lymphatics to the pathogenesis of lung emphysema we used a mouse model of cigarette smoke (CS)-induced emphysema, and a...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-10 | PXD031413 | Pride
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