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ProteomicsProximity Labeling and Genetic Screening Reveals the Role of DSG2/Siglec-9 Axis in Suppressing Macrophage Phagocytosis
In current study, we have established a combined strategy using proximity labeling and genetic screening to identify the cellular ligands of Siglec-9. Our use of proximity labeling using APEX2 fusion proteins followed by quantitative proteomics allowed us to efficiently label and enrich cell surface...
ORGANISM(S): Homo sapiens (Human) 
2024-12-23 | PXD051557 | Pride
Siglec-9 Apex2 Dsg2 Proximity label 
GenomicsRas-induced epigenetic inactivation of RRAD promotes glucose uptake in a human ovarian cancer model (RRBS-Seq]
Ras-related associated with diabetes (RRAD) is a small Ras-related GTPase that is frequently inactivated by DNA methylation of the CpG island in its promoter region in cancer tissues. However, the role of the methylation-induced RRAD inactivation in tumorigenesis remains unclear. In this study, the ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-55566 | biostudies-arrayexpress
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
ProteomicsInvestigating the impact of GalNAc-T2 overexpression on proteomics and glycoproteomics in lung cell
GalNAc-T2 was identified as a novel antiviral factor that promotes viral clearance and contributes to reduced disease severity.This project aimed to investigate the impact of GalNAc-T2 overexpression on proteomics and glycoproteomics in lung cell. We employ SILAC labeling, lectin-based affinity enri...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD051101 | Pride
Galnac-t2 Glycoproteomics Lung Homo sapiens 
UnknownDynamic Variation of Amino Acid Contents and Identification of Sterols in Xinyang Mao Jian Green Tea.
Not available
S-EPMC9182030 | biostudies-literature
UnknownRadiomics-Based Machine Learning Classification Strategy for Characterization of Hepatocellular Carcinoma on Contrast-Enhanced Ultrasound in High-Risk Patients with LI-RADS Category M Nodules.
Not available
S-EPMC11188750 | biostudies-literature
ProteomicsTudor-based Proteomic Strategy Pan-specifically Enriches and Identifies Protein Arginine Methylation
In current study, we developed a molecular affinity strategy based on the Tudor domain of SMN, a naturally occurring methylarginine reader protein, for comprehensive proteomic profiling of cellular arginine methylation. We demonstrated that the Tudor domain-based approach exhibits broad specificity ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD053390 | Pride
Proteomics Arginine methylation Molecular affinity-enrichment method Eif3d 
UnknownM<sup>6</sup>A Demethyltransferase FTO Attenuates Meniscus Degeneration and Osteoarthritis via Orchestrating Autophagy and Energetic Metabolism.
Not available
S-EPMC11884582 | biostudies-literature
UnknownEfficacy of Subantimicrobial Dose Doxycycline for Moderate-to-Severe and Active Graves' Orbitopathy.
Not available
S-EPMC4499606 | biostudies-literature
UnknownReactive Oxygen Species-Responsive Ferrocene Nanoparticles Delivering Small Interfering RNA Targeting NOP2/Sun RNA Methyltransferase Family Member 2 for Gastric Cancer Therapy.
Not available
S-EPMC12120247 | biostudies-literature
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