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TranscriptomicsEpigenome analysis of human epidermal and dermal samples with aging and sun exposure
Genome wide DNA methylation profiling of epidermal and dermal samples obtained from sun-exposed and sun-protected body sites from younger (<35 years old) and older (>60 years old) individuals. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles acro...
ORGANISM(S): Homo sapiens 
2015-03-23 | E-GEOD-51954 | biostudies-arrayexpress
ProteomicsDeep proteomic and phosphoproteomic profiling of neuroblastoma treated with XPO1 inhibitor Selinexor
Neuroblastoma accounts for 15% of cancer-related deaths in children, highlighting an unmet need for novel therapies. Selinexor is a small molecule inhibitor of XPO1 that shuffles cargo proteins with a nuclear export sequence, many of which are essential for cancer growth and cell maintenance, from t...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026454 | Pride
Tmtpro Phosphoproteome Selinexor Xpo1 Neuroblastoma Proteome 
TranscriptomicsWhole genome expression data from pre-auricular and post-auricular skin tissues
Photoaging is cumulative damage that is caused by chronic, repeated solar radiation exposure to skin. Its molecular mechanisms are poorly understood at the level of global gene expression.This study set out to uncover genes and functional modules involved in photoaging at the level of transcription,...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-38308 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
ProteomicsProteomic Profiling Identifies Novel Diagnostic Biomarkers and Molecular subtypes for Mucinous Tubular and Spindle Cell Carcinoma of the Kidney
Mucinous tubular and spindle cell carcinoma (MTSCC) is a relatively rare renal epithelial neoplasm resembling type 1 papillary renal cell carcinoma (PRCC) morphologically and immunohistochemically. The accurate diagnosis of MTSCC remains a challenge. Here, by using proteomic profiling, we characteri...
ORGANISM(S): Homo sapiens (Human) 
2022-02-11 | PXD027972 | Pride
Mucinous tubular and spindle cell carcinoma Immunohistochemistry Proteomic Kidney 
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
UnknownFive New Hypocrealean Species from Algae and Sediment in the Intertidal Zones of China.
Not available
S-EPMC12295223 | biostudies-literature
UnknownStructural insights into SUN-KASH complexes across the nuclear envelope.
Not available
S-EPMC3463262 | biostudies-literature
ProteomicsIdentification of missing proteins in the proteome atlas of multiple healthy human tissues
We re-analyzed the deep proteome atlas of 29 paired healthy human from the published paper (Wang, Dongxue, et al. Molecular systems biology 15.2 (2019)) to identify missing proteins.
ORGANISM(S): Homo sapiens (Human) 
2020-11-17 | PXD021391 | Pride
Chpp Open-pfind Missing proteins Mutiple tissues 
ProteomicsProteomics-based identification of potential therapeutic targets of artesunate in a lupus nephritis MRL/lpr mouse model
A total of 6527.0 proteins were identified in the First Affiliated Hospital of Sun Yat sen University, of which 5732.0 proteins contained quantitative information. If we take 1.5 times as the differential expression change threshold and t-test p-value < 0.05 as the significance threshold, we found t...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD046815 | Pride
Lupus nephritis artesunate tmt-based quantitative proteomics 
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