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ProteomicsRadiation resistance comparable to natural extremophiles achieved through experimental evolution
Recent human exploitation of high-level sources of ionizing radiation (IR) has generated a corresponding need to understand the effects of IR on living systems. Part of that research has focused on the astonishing capacity of some organisms to survive extraordinary levels of IR exposure. Using exper...
ORGANISM(S): Deinococcus radiodurans Escherichia coli 
2021-09-10 | PXD024784 | Pride
E coli Radiation D radiodurans Oxidation 
TranscriptomicsRac1-Induced Connective Tissue Growth Factor regulates Connexin 43 and N-Cadherin Expression in Atrial Fibrillation
Objectives: We studied the signal transduction of atrial structural remodelling that contributes to the pathogenesis of atrial fibrillation (AF). Backround: Fibrosis is a hallmark of arrhythmogenic structural remodelling but the underlying molecular mechanisms are incompletely understood. Methods: W...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-14975 | biostudies-arrayexpress
UnknownCENP-A is essential for cardiac progenitor cell proliferation.
Not available
S-EPMC3979910 | biostudies-literature
MetabolomicsDissolved organic matter produced by Thalassiosira pseudonana
Phytoplankton are significant producers of dissolved organic matter (DOM) in marine ecosystems but the identity and dynamics of this DOM remain poorly constrained. Knowledge on the identity and dynamics of DOM are crucial for understanding the molecular-level reactions at the base of the global carb...
2014-12-12 | MTBLS144 | MetaboLights
ProteomicsAKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture
In addition to driving tumorigenesis, oncogenes can create metabolic vulnerabilities in cancer cells. Here, we tested how the oncogenes AKT and MYC affect the ability to shift between respiration and glycolysis. Using immortalized mammary epithelial cellsMCF10A, we discovered constitutively active A...
ORGANISM(S): Homo sapiens (Human) 
2020-03-19 | PXD015122 | Pride
Oxidative culture Proteomics Metabolomics Myc Galactose Catalase Ros Akt Oxidative stress Cancer cells survival; 
UnknownDevelopment of Advanced Imaging Criteria for the Endoscopic Identification of Inflammatory Polyps.
Not available
S-EPMC4816089 | biostudies-literature
ProteomicsComparative proteomic analysis of self-compatible Turnera mutants suggests Glutathione S-transferase 8 is involved in overcoming S-morph female self-incompatibility response. Part1 WT S- vs L-morph samples
Comparative proteomic analysis of the S- and L-morphs of WT Turnera subulata and Turnera joelii.
ORGANISM(S): Turnera joelii Turnera subulata 
2025-12-08 | PXD057029 | Pride
Turnera Self-incompatibility Pollen 
UnknownSupported decision-making with persons with dementia: a scoping review protocol in partnership with lived experts.
Not available
S-EPMC11298746 | biostudies-literature
UnknownCharacterization of gene-activated human acid-beta-glucosidase: crystal structure, glycan composition, and internalization into macrophages.
Not available
S-EPMC2782181 | biostudies-literature
UnknownValidation of the American Joint Committee on Cancer Eighth Edition Staging of Patients With Metastatic Cutaneous Melanoma Treated With Immune Checkpoint Inhibitors.
Not available
S-EPMC7944385 | biostudies-literature
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