Sort   by:  
 Page size 
ProteomicsQuantitative SILAC phosphoproteomics and proteomics of HL60 cells treated with covalent CDK7 inhibitor SY351
Using the covalent inhibitor SY-351 and quantitative SILAC phosphoproteomics, we identified CDK7 kinase substrates in human cells. We performed a double-label SILAC phosphoproteomics experiment, in which we metabolically labeled HL60 cells with light labeled (Lys0, Arg0) or heavy labeled (Lys8, Arg...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-06-10 | MSV000085575 | MassIVE
ProteomicsCDK7-CDK11 axis in spliceosome regulation and pre-mRNA splicing – phosphopeptides dataset
Cyclin-dependent kinase 11 (CDK11) is essential for the regulation of pre-mRNA splicing via phosphorylation of the core spliceosome component SF3B1. This phosphorylation is a marker of the catalytically active spliceosomes thus it is important to identify the mechanisms that regulate CDK11 itself. H...
ORGANISM(S): Homo sapiens (Human) 
2025-12-29 | PXD062535 | Pride
Ots964 Sf3b1 Cdk7 Cdk11 Splicing Sy351 
ProteomicsCDK7-CDK11 axis in spliceosome regulation and pre-mRNA splicing – BioID dataset
Cyclin-dependent kinase 11 (CDK11) is essential for the regulation of pre-mRNA splicing via phosphorylation of the core spliceosome component SF3B1. This phosphorylation is a marker of the catalytically active spliceosomes thus it is important to identify the mechanisms that regulate CDK11 itself. H...
ORGANISM(S): Homo sapiens (Human) 
2025-12-29 | PXD068896 | Pride
Ots964 Sf3b1 Cdk7 Cdk11 Splicing Sy351 
Sort   by:  
 Page size